Arkray, Inc.

Kyoto Daiichi Kagaku Co., Ltd.

Sekisui Medical Co., Ltd.

Toshikatsu Sakai

Koji Sugiyama

Akira Sezaki

Takeshi Takagi

Nobuo Kato

Yoshiki Tani

Yasuyoshi Sakai

Kaori Ishimaru

Takuya Yotani

Takayuki Oka

Masayuki Yagi

Hiroshi Fukuya

Tatsuo Kamata

Yoshikiyo Hongo

Takanori Kamada

Makoto Takahara

Satoshi Cyousa

Suguru Yoshida

Yoshihiro Nomura

Kazuki Ishikawa

Takeshi Asami

A liquid chromatography apparatus is provided with a sample preparation unit, a column that separates components of a sample, an eluent supplier that includes a feeder for supplying eluents to the column, a flow path directional valve capable of introducing fixed amounts of the sample and the eluents to the column, an analyzer for analyzing a test solution composed of the sample components separated by the column and one of the eluents, and a controller, wherein the eluent supplier supplies the eluents to the flow path directional valve in an unmixed state. As a result of employing this configuration, analysis time is shortened and eluent consumption is reduced.

Liquid chromatography apparatus and liquid chromatography

An analyzing device includes a feeder connected to a container in which a sample is contained for sucking the sample from the container and feeding the sample, and a controller for performing control for feeding from the feeder to a measurer. In measuring the sample, the controller performs control so that results of a plurality of times of measurement are obtained with respect to the single container in which the sample is contained, without changing the container. This arrangement allows quick accuracy check.

Analyzing device and method for controlling same

The present invention relates to a liquid chromatography apparatus X, which is provided with a deaerator. The liquid chromatography apparatus X is further provided with a dissolved oxygen density adjusting means for maintaining a density of dissolved oxygen in an eluting solution to be supplied to a columnconstant. Preferably, the dissolved oxygen density adjusting means is configured so as to adjust the density of the dissolved oxygen in the eluting solution by adjusting a degree of decompression in a decompression space of the deaeratorbased on a measurement result by temperature measurement meansA,B, andC for measuring the temperature of the eluting solution.

Liquid chromatograph

When the concentration of glycated hemoglobin is measured, a plurality of wavelengths are selected as measurement wavelengths from the wavelength range of 400 to 450 nm. Preferably, by use of a liquid chromatography, at least the light of different peak wavelengths in the wavelength range of 415 to 430 nm are continuously or intermittently received to obtain a three dimensional chromatogram having as variables the wavelength, the elution time and the amount of detection. The concentration of glycated hemoglobin is calculated based on this three dimensional chromatogram.

Method of measuring glycated hemoglobin concentration and concentration measuring apparatus

The present invention relates to a method and an apparatus that measure the concentration of glycated hemoglobin by an optical technique. A wavelength in which the molecular extinction coefficient of oxyhemoglobin agrees or substantially agrees with the molecular extinction coefficient of deoxyhemoglobin is adopted as a measurement wavelength. Preferably, the measurement wavelength is set at from 417 to 421 nm. In the present invention, the concentration of glycated hemoglobin is measured by making use of column chromatography and of using a sample prepared from red blood cells in blood.

Method of measuring glycated hemoglobin concentration

Fructosyl amino acid oxidase, process for producing the same, and method

A novel fructosyl amino acid oxidase derived from genus Fusarium, which is active on both of fructosyl lysine and fructosyl valine, a process for producing the enzyme, an assay of an amadori compound using the enzyme, a reagent or a kit containing the enzyme is provided.

Fructosyl amino acid oxidase

Growing community of inventors

Kyoto, Japan

Toshikatsu Sakai