Shionogi Company Limited

Eli Lilly and Company

Heraeus Electronite Japan, Ltd.

Toshihiro Ogura

Toyohiko Takeda

Peter L Oren

Akihiro Ono

Teruo Sakamoto

Yasushi Takagishi

Neil R Anderson

Toshiro Fujii

Kinzaburo Noda

Sadao Kawai

Shunji Nagata

Hiroaki Kosaka

Masaki Ina

Kenji Sasaki

Disclosed herein is a method of sequentially and continuously determining the concentrations of carbon, hydrogen, and nitrogen in molten steel using a single apparatus. Disclosed also herein are a method and an apparatus for determining trace amounts of carbon in molten steel which are the specialized application of the principle used for the above-mentioned method. Said method comprises bubbling through molten steel a carrier gas selected according to any specific element to be determined in molten steel, recovering the carrier gas containing the specific element, circulating or passing the recovered carrier gas through a gas circulating circuit so that the concentration of the specific element in the carrier gas reaches an approximate or complete equilibrium with the concentration of the specific element in molten steel, determining the concentration of the specific element by the means to determine the concentration of one or more specific elements, (and in the case of determination of several elements) discharging the carrier gas from the gas circulating circuit and repeating said steps with a renewed carrier gas to determine the remaining elements to be determined.

Method and apparatus for sequentially and continuously determining

A superior enteric formulation of the antidepressant drug, duloxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.

Duloxetine enteric pellets

A favorable sustained-releasing property is given to granular preparations by incorporating therein at least one C.sub.16 -C.sub.18 saturated fatty acid and/or metal salts thereof at a rate of 10-50% of the total weight of the dosage form. The disclosed dosage form releases the active ingredient both in a low pH region of the stomach and in a high pH region of the intestine at an appropriate rate.

Sustained-release granular pharmaceutical preparations

Highly effective and orally administrable sustained-release preparation of an antihypertensive agent, pinacidil (N'-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine) comprising a rapid-release and a slow-release component at a ratio of about 7:3 to about 1:9 by pinacidil weight.

Sustained-release preparation of pinacidil

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Osaka, Japan

Toshihiro Ogura