Senju Pharmaceutical Co., Ltd.

Takeda Chemical Industries, Inc.

Toshiharu Tsuboi

Tadashi Makino

Takahiro Ogawa

Koji Doi

Noriko Watanabe

Mitsunori Waki

Masayoshi Matsuoka

Ken-ichi Yoshida

Nobuyoshi Shimizu

Motoi Aoe

Mitsuyoshi Isaka

Tetsunobu Udaka

An agent for the prophylaxis and treatment of disturbance of visual function, which comprises a compound of the formula �I! ##STR1## wherein A ring is optionally substituted;

Agent for prophylaxis and treatment of disturbance of visual function

According to the present invention, there are provided immunosuppressive-activity potentiating compositions which comprise a phosphoric acid diester compound represented by the following formula �I!: ##STR1## (R.sub.1 and R.sub.2 are the same or different and represent individually a hydrogen atom or methyl group) or its pharmacologically acceptable salt, and the immunosuppressive-activity potentiating compositions can suppress effectively acute rejection after transplantation.

Immunosuppressive-activity potentiating compositions

Provided are a solid pharmaceutical preparation which contains disodium adenosine triphosphate together with a vitamin B.sub.1 salt or the like and a method of treatment of human asthenopia by orally administering the same. Also provided are a solid pharmceutical preparation according to the abovementioned preparation, which further contains a low-melting fat- or oil-like substance and has an improved stability of disodium adenosine triphosphate, and a method of producing the same.

Solid pharmaceutical preparation and method of producing same

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Settsu, Japan

Toshiharu Tsuboi