Kyushu University

Mochida Pharmaceutical Co., Ltd.

Kurume Research Park Co., Ltd.

Sysmex Corporation

Kobe University

Hisayama Research Institute for Lifestyle Diseases

Toshiharu Ninomiya

Takashi Yano

Satoru Kuhara

Yutaka Kiyohara

Yoshinori Katakura

Kazuhiro Fujita

Jun Hata

Naoko Mukai

Tomoyuki Ohara

Katsuhiro Murakami

Yoichiro Hirakawa

Yasuhiro Irino

A disease risk assessment apparatus () includes an assessment unit () for assessing the risk of developing dementia in a subject, based on the concentration of an amino acid in the blood of the subject. The amino acid includes at least one selected from the group consisting of histidine, phenylalanine, leucine, isoleucine, methionine, threonine, glycine, glutamine, lysine, asparagine, homocysteine, cystathionine, S-adenosylmethionine, and S-adenosylhomocysteine.

Disease risk assessment apparatus, disease risk assessment method, computer readable medium, and food for dementia prevention

The present invention provides the following: a cardiovascular disease primary prevention agent, which comprises as the active ingredient at least one selected from the group consisting of EPA, salts thereof, and esters thereof and is for lowering the risk of cardiovascular disease by administration to subjects having a blood (serum or plasma) hs-CRP level of 1.0 mg/L or higher in spite of no history of cardiovascular disease; a combination marker comprising the blood hs-CRP value and serum EPA/AA ratio for evaluating the primary risk of cardiovascular disease in subjects having no history of cardiovascular disease; and a method for extracting subjects with high risk of cardiovascular disease and/or a method for preventing cardiovascular disease.

Cardiovascular disease primary prevention agent for patients having high blood levels of high-sensitivity C-reactive protein

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Fukuoka, Japan

Toshiharu Ninomiya