National Institute of Advanced Industrial Science and Technology

Shionogi Company Limited

Hokkaido University

System Instruments Co., Ltd.

Toshiharu Kuroda

Michio Horiuchi

Hiroshi Yamazaki

Shinichiro Nishimura

Yoshiaki Miura

Yasuro Shinohara

Koichi Chiba

Yoko Kita

Mika Nakano

Hiroaki Motoki

Yanbei Zhu

In an embodiment, control is performed to operate a three-way valve in accordance with a reaching ratio of pH adjustment. When process of certain steps is performed, bubbles of ammonia generated in a nebulizer can be extruded by air so as to be injected from an injection port together with aqua ammonia remaining in the nebulizer. Therefore, the pH adjustment can be performed while a large amount of bubbles of ammonia are prevented from being generated in the nebulizer.

Automatic pH adjustment device

To provide an autoanalyzer for analyzing a sugar chain contained in a biological sample, in particular, serum. Namely, it is intended to provide a method of analyzing a sugar chain in a sample, which comprises the following steps: A) the sugar chain-releasing step of releasing the sugar chain in the sample; B) the detection sample-preparing step of preparing the released sugar chain for detection; and, in the case of conducting mass spectrometry using a plate, C) the step of forming a plate for the mass spectrometry having the captured sugar chain dotted thereon which comprises the step of providing the tagged sugar chain sample solution obtained in the step B) on a collection plate; and, if required, the step of conducting an operation in a solid phase support-enclosed plate to form the plate for mass spectrometry; and D) the step of analyzing the sugar chain to be assayed.

Apparatus for auto-pretreating sugar chain

Growing community of inventors

Tokyo, Japan

Toshiharu Kuroda