Sankyo Company, Limited

Nippon Kayaku Kabushiki Kaisha

Ciba-geigy Corporation

Toshiaki Yanai

Kazuo Sato

Keiji Tanaka

Anthony Cornelius O'Sullivan

Akio Saito

Shinji Yokoi

Bruno Frei

Takao Kinoto

Akira Nishida

Kiyoshi Konishi

Takao Okazaki

Seigo Iwado

Shuji Takahashi

Hideo Takeshiba

Yoshihisa Tsukamoto

Toshimitsu Toyama

Mikio Yanagi

Hisaki Kajino

Shigeru Mio

Akio Masui

Yasuhito Kato

Tetsuya Toya

Hiroyasu Sugizaki

Yoshimi Yajima

Tetsuo Watanabe

Hidetoshi Shirakura

Seiichirou Kodama

Yoshihiro Sawada

Noritoshi Kitano

Katsuhiko Kawakubo

Junzo Tobitsuka

Teruomi Jojima

Toyokuni Honma

Soji Sugai

Kinji Tanizawa

Reiji Ichinose

Masahiro Shindo

Shinya Niimi

Hari B Mereyala

Dimethylfurancarboxyanilide derivatives

A dimethylfurancarboxyanilide compound of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each is hydrogen, (C.sub.2 -C.sub.6)-alkyl, (C.sub.3 -C.sub.6)-cycloalkyl, (C.sub.3 -C.sub.6)-alkenyl, (C.sub.2 -C.sub.6) alkynyl, (C.sub.1 -C.sub.3)-halogenoalkyl, (C.sub.2 -C.sub.6)-alkoxy, (C.sub.1 -C.sub.6)-alkoxy- (C.sub.1 -C.sub.6)-alkyl, cyano, substituted amide, (C.sub.1 -C.sub.6)-alkoxy-carbonyl, benzoyl which is unsubstituted or has 1 to 2 substituents, benzoylamino which is unsubstituted or has 1 to 2 substituents; (C.sub.2 -C.sub.6)-alkanoylamino, (C.sub.3 -C.sub.6)-cycloalkylcarbonylamino, benzyl which is unsubstituted or has 1 to 2 substituents, phenyl which is unsubstituted or has 1 to 2 substituents, or (C.sub.1 -C.sub.6)-alkoxycarbonyl-(C.sub.2 -C.sub.5)-alkenylene; and R.sup.1 and R.sup.2 do not both represent hydrogen at the same time. A wood preservative containing the dimethylfurancarboxyanilide compound as an active ingredient. A method of preserving wood by applying the dimethylfurancarboxyanilide compound to wood. A wood preservative composition in which the dimethylfurancarboxyanilide compound is combined with at least one of 3-bromo-2,3-diiodo-2-propenylethylcarbamate, 3-iodo-2-propynylbutylcarbamate and 4-chlorophenyl-3-iodopropargylformal.

Wood preservative compositions containing dimethylfurancarboxyanilide

13-Substituted milbemycin derivatives having the formula (I): ##STR1## wherein: R.sup.1 is methyl, ethyl, isopropyl or sec-butyl;

13-substituted milbemycin derivatives, their preparation and their use

A novel hydrazine derivative and a pesticidal composition containing the hydrazine derivative as the effecting ingredient. The hydrazine derivative show high pesticidal activity against harmful pests which are resistant to known pesticides such as organophosphorus pesticides, pyrethroids, etc., especially against Lepidoptera harmful pests such as Plutella xylostella, Spodoptera litura, Cnaphalocrocis medinalis, Adoxophyes orana, etc., and is effective for controlling harmful pests in paddy field, upland field, orchard, forest or places to be kept environmentally hygienic.

Hydrazine derivative and pesticidal composition comprising said

Compounds having a 16-membered macrolide ring, and related to the milbemycins and avermectins, with substituents at positions 5.13, 25 and optionally also 23, have acaricidal, insecticidal and anthelmintic properties. They are useful for treating various pests in plants and animals.

Macrolide compounds, their preparation and their use

A novel hydrazine derivative and a pesticidal composition containing the hydrazine derivative as the effecting ingredient. The hydrazine derivative show high pesticidal activity against harmful pests which are resistant to known pesticides such as organophosphorus pesticides, pyrethroids, etc., especially against Lepidopters harmful pests such as Plutella xylostella, Spodoptera litura, Cnaphalocrocis medinalis, Adoxophyes orana, etc., and is effective for controlling harmful pests in paddy field, upland field, orchard, forest or places to be kept environmentally hygienic.

New hydrazine derivative and pesticidal composition comprising said

Compounds having the formula (I) ##STR1## wherein: R.sup.1 is methyl, ethyl or isopropyl; R.sup.2 is alkyl, aralkyl, cycloalkyl, cycloalkylmethyl, aryl, heterocyclic, or heterocyclic-substituted thio; R.sup.3 is hydrogen, methyl or ethyl; or R.sup.2 together with R.sup.3 is --(CH.sub.2).sub.n --, wherein n is 3,4 or 5; and A is aromatic heterocyclic; and salts thereof, are valuable agricultural and horticultural anthelmintic, acaricidal and insecticidal agents.

13-(substituted thio)acetoxymilbemycin derivatives, their preparation

Compounds with acaricidal, insecticidal and anthelmintic activities have the formula: ##STR1## wherein: --X--Y-- is selected from the group consisting of --CH.sub.2 --CH.sub.2 --, --CH.sub.2 --CHOH--, --CH.dbd.CH--, and --CH.sub.2 --C(.dbd.O)--;

13-Hydroxy-5-ketomilbemycin derivatives are prepared by oxidizing a 5-ketomilbemycin with selenium dioxide in the presence of a lower aliphatic carboxylic acid. A range of new 13-acyloxy-5-ketomilbemycins and a method of preparing them are also disclosed.

Process for preparing milbemycin derivatives and certain novel compounds

Compounds having a 16-membered macrolide ring, and related to the milbemycins and avermectins, with substituents at positions 5, 13, 25 and optionally also 23, have acaricidal, insecticidal and anthelmintic properties. They are useful for treating various pests in plants and animals.

The present invention relates to novel compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, a silyl group or an acyl group,

Pesticides

Derivatives of milbemycins D, A.sub.3 and A.sub.4 and of the corresponding sec-butyl compound have a halogen atom at the 13-position; at the 5-position, they have an oxygen (keto) atom, an oxime group or a substituted oxime group. They may be prepared from known compounds by any appropriate combination of halogenation, ketonization and oximation.

13-Halomilbemycin derivatives, their preparation and compositions

8,9 and/or 14,15 epoxidized and 5-acylated milbemycins and avermectins are prepared from the parent milbemycins and avermectins by epoxidation and acylation (in either order). They have enhanced anthelmintic, acaricidal and insecticidal activities.

Antiparasitic milbemycin and avermectin derivatives

Growing community of inventors

Shiga, Japan

Toshiaki Yanai