Hiroshima University

Altan Co., Ltd.

Tokyo University of Science Foundation

Toru Tsuji

Tadashi Shimamoto

Yoshiaki Nakai

Shigeo Fujimori

Etsuko Miyamoto

Takemasa Sakaguchi

Masamichi Ishizaka

Yasushi Okinaka

A method for analyzing biomolecular interactions, which method can be carried out without performing affinity selection using an immobilized bait, is provided. mRNA portions of assignment molecules that interacted with each other are linked together by annealing via a DNA linker for linking mRNA portions of assignment molecules together, the DNA linker comprising, at the 5'-end, an mRNA-complementary region complementary to a sequence at the 5&#x2032;-end of each mRNA portion, and, at the 3&#x2032;-end, a self-complementary region complementary between molecules of the DNA linker, the DNA linker being phosphorylated at the 5&#x2032;-end.

Constitution of tool for analyzing biomolecular interaction and analysis method using same

Provided herein is a method for disinfection or infection control against a non-enveloped virus using a composition including, as an active ingredient, a persimmon extract containing tannin from an astringent fruit of a plant of the genus, such as the plant. The non-enveloped virus is a non-enveloped virus belonging to the genus Betanodavirus, Aquavirnavirus, Ranavirus, Enterovirus, Mastadenovirus, Vesivirus, or Rotavirus. In certain embodiments, the persimmon extract is prepared by heating a squeezed juice or an extract from an astringent fruit of a plant of the genus, or obtained by treating a squeezed juice or an extract from an astringent fruit of the plant of the genuswith an alcohol, in order to inactivate an enzyme contained therein. The persimmon extract may also contain at least condensed tannin.

Method for disinfection or infection control against a non-enveloped virus

An anti-norovirus agent that has high norovirus-inactivating activity and is safe for the human body, and an anti-norovirus composition that contains the anti-norovirus agent and is useful for disinfection and infection control against the norovirus. The anti-norovirus agent includes, as an active ingredient, an extract from a plant of the genuscontaining tannin (hereinafter referred to as a 'persimmon extract'), preferably a persimmon extract produced by heating squeezed juice or an extract from the fruit of a plant of the genusor treating the squeezed juice or the extract with an alcohol. The anti-norovirus composition contains the anti-norovirus agent and at least one selected from the group consisting of alcohols, surfactants, antimicrobial agents, humectants, and cosmetic fats and oils, and preferably further containing an organic acid, such as citric acid, and/or a salt thereof or vitamin C.

Method of disinfection or infection control against norovirus

Provided is an anti-norovirus agent that has high norovirus-inactivating activity and is safe for the human body, and an anti-norovirus composition that contains the anti-norovirus agent and is useful for disinfection and infection control against the norovirus. The anti-norovirus agent includes, as an active ingredient, an extract from a plant of the genuscontaining tannin (hereinafter referred to as a 'persimmon extract'), preferably a persimmon extract produced by heating squeezed juice or an extract from the fruit of a plant of the genusor treating the squeezed juice or the extract with an alcohol. The anti-norovirus composition contains the anti-norovirus agent and at least one selected from the group consisting of alcohols, surfactants, antimicrobial agents, humectants, and cosmetic fats and oils, and preferably further containing an organic acid, such as citric acid, and/or a salt thereof or vitamin C.

Growing community of inventors

Tokyo, Japan

Toru Tsuji