Daiichi Sankyo Company, Limited

Honda Motor Co., Ltd.

Reika Kogyo Kabushiki Kaisha

Reica Corporation

Sumitomo Mitsubishi Silicon Corporation

Other

Honda Giken Kogyo Kabushiki Kaisha

Mitsui Engineering and Shipbuilding Company Limited

Iida Denki Kogyo Co., Ltd.

Toda Corporation

Toru Taniguchi

Shinji Tanaka

Toshikazu Nakamura

Yasuyuki Ogawa

Keiji Saito

Osamu Iwamoto

Katsuyoshi Nakajima

Kaori Ito

Nobuya Kurikawa

Eriko Kioi

Kazumasa Aoki

Satoshi Shibuya

Wataru Saitoh

Momoko Ogitani

Natsumi Nishihama

Tsuyoshi Mikkaichi

Seiji Harada

Kazumi Miyashita

Kazutomo Nishida

Isoroku Ono

Hiroaki Kojima

Seiko Nagata

Etsuro Morita

Fumihiko Yoshida

Satoshi Matagawa

Mitsuhiro Endo

Keisuke Yoshida

Yoshikazu Yamada

Masahiro Nakagawa

Hiroshi Moriyama

Yasutake Ryu

Makoto Yonezawa

Shoko Yoshida

Kouichi Uoto

Yuuichi Sugimoto

Naoya Kumagai

Masanori Fujinuma

Masaki Miyazaki

Koji Tada

Hitoshi Matsumoto

Masaki Setoguchi

Shin-ichi Nakao

Akitake Yamaguchi

Hiroshi Mochizuki

Daisuke Suzuki

Yuzuru Tahara

Takanori Wakabayashi

Yoshinobu Kawano

Yasuo Hatate

Yuji Tachikawa

Makoto Ukegawa

Ayao Siseki

Shingo Shimizu

Seiki Osanai

Koji Matsuno

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: A: e.g., Benzene, E: e.g., —CH—, G: e.g., a 5-membered aromatic heterocyclic ring, X: e.g., cyclohexane, J: e.g., a 5-membered aromatic heterocyclic ring, Y: e.g., a phenyl group, R, R, R: e.g., a halogen atom, R: e.g., a C1-C6 alkyl group, R: e.g., a hydrogen atom, R, R, R, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, n, n, n: e.g., 1.

Compound having cyclic structure

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R: e.g., a C1-C6 alkyl group; R: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R: e.g., a C1-C6 alkyl group.

Griseofulvin compound

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below:R: e.g., a C1-C6 alkyl group; R: a C1-C6 alkyl group;A: e.g., an oxygen atom; and R: e.g., a C1-C6 alkyl group.

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below:A: e.g., Benzene, E: e.g., &#x2014;CH&#x2014;, G: e.g., a 5-membered aromatic heterocyclic ring, X: e.g., cyclohexane, J: e.g., a 5-membered aromatic heterocyclic ring, Y: e.g., a phenyl group, R, R, R: e.g., a halogen atom, R: e.g., a C1-C6 alkyl group, R: e.g., a hydrogen atom, R, R, R, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, n, n, n: e.g., 1.

Provided is a bi-fuel engine including a pressure supply passage extending from a crankcase chamber, and branching into a first branch passage and a second branch passage at a branching portion, a gas fuel valve provided in the gas fuel supply passage and connected to the first branch passage so that the gas fuel supply passage may be opened when pressure is supplied to the gas fuel supply passage, and may be closed when pressure is not supplied to the gas fuel supply passage, a liquid fuel pump provided in the liquid fuel supply passage and configured to feed the liquid fuel under pressure to the intake system by a pulsating pressure supplied via the second branch passage, and a switch valve provided in the branching portion to switch between the first and second branch passages for conducting pressure supplied from the pressure source via the pressure supply passage.

Bi-fuel engine

A compound that inhibits interaction between murine double minute 2 (Mdm2) protein and p53 protein and exhibits anti-tumor activity is provided. The present invention provides a dispiropyrrolidine derivative represented by the following formula (1), which has various substituents, inhibits interaction between Mdm2 protein and p53 protein and exhibits anti-tumor activity, wherein R, R, R, ring A, and ring B in formula (1) respectively have the same meanings as defined in the specification. 

Dispiropyrrolidine derivatives

A carburetor provided on an intake pipe is disclosed. The carburetor includes a rotary cock attached to a fuel chamber. The cock is used for opening and closing fuel channels and drain channels. The cock has a rotational axis inclined relative to the central axis of the intake pipe.

Carburetor and general purpose engine

A method of manufacturing a semiconductor wafer, including a step of differentiating the glossiness of a front surface from that of a rear surface of the wafer by holding the semiconductor wafer in a wafer holding hole formed in a carrier plate, and simultaneously polishing a front and back surface of said semiconductor wafer by driving said carrier plate to make a circular motion associated with no rotation on its own axis within a plane parallel with a surface of said carrier plate between a pair of polishing members disposed to face to each other, by using an abrasive body with a semiconductor wafer sink rate different in polishing from that of an abrasive body for one of a polishing member on an upper surface plate and a polishing member on a lower surface plate so as to simultaneously polish both the front and rear surfaces of the semiconductor wafer, or differentiating by differentiating the rotating speed of the upper surface plate from that of the lower surface plate.

Method of manufacturing semiconductor wafer

Air filtered through a filter element in a case is supplied via an air outlet port to a carburetor. Bottom plate of the case includes a support frame section bulging inwardly of the case. The support frame section includes a peripheral wall surrounding the periphery of the outlet port, a plurality of posts extending upward from the peripheral wall, and a canopy portion of a plate shape provided on the upper ends of the posts. Interior of the case and the outlet port are in communication with each other via a space between the posts, and the canopy portion covers the whole opening area of the outlet port.

Air cleaner for internal combustion engine

A fuel supplying apparatus is configured to supply a gas engine with gas fuel in such a manner that tar separated from the gas fuel is guided to the engine. The apparatus includes a primary regulator and a secondary regulator formed integrally with the primary regulator. The primary regulator communicates with the secondary regulator through a gas passage. The secondary regulator is disposed below the primary regulator. The secondary regulator has a gas inlet for taking in the gas fuel and the tar that have passed from the primary regulator through the gas passage. The secondary regulator has an orifice disposed below the gas inlet for discharging the gas fuel and the tar. The tar separated from the gas fuel flows from the primary regulator through the gas passage and the gas inlet into the secondary regulator and discharged out of the orifice into the engine.

Fuel supplying apparatus for gas engine

An oil level detection device for an internal combustion engine, which comprises: a housing permitting entry therein of oil; a float provided within the housing and vertically movable with the oil entered in the housing; a switch for performing switching operation in response to the vertical movement of the float within the housing; protrusions provided, on the upper surface of the float, for preventing the float from sticking to the ceiling of the housing due to viscosity of the oil; and protrusions provided, on the bottom of the housing, for preventing the float from sticking to the bottom of the housing due to viscosity of the oil.

Oil level detection device for internal combustion engine

Growing community of inventors

Tokyo, Japan

Toru Taniguchi