Cybio Ag

Torsten Rausch

Thomas Moore

Peter Zimmermann

Wolfgang Krämer

Hartmut Köberich

Simon Renard

Dirk Philipp

Gerd Heiβe

Gerd Heibe

An arrangement and process for calibrating and/or equilibrating single-channel and multi-channel liquid handling devices, wherein a dispensing volume of a liquid is dispensed via the dispensing channels of a liquid handling device into a measurement chamber of a measurement chamber carrier, each measurement chamber being associated with a dispensing channel, and the individual measurement chambers are hermetically sealed successively relative to the environment and are connected to a pressure chamber under an operating pressure so that an equilibrium pressure occurs that is relevant to the respective dispensing volume.

Process and arrangement for calibrating and/or equilibrating single-channel and multi-channel liquid handling devices

Procedure for equilibration of the delivery volumes of a multi-channel metering apparatus with an arrangement of independently controlled dispensing channels-.n, delivering individual volumes of dispensing fluid to cavities-.n.n, where measured values relevant to the individual delivery volumes are measured for the same control value and from which an adjustment value is specified with a tolerance band and the control value is adjusted for dispensing channels-.n, the measured values of which lie outside the tolerance band. The invention also applies to an apparatus for implementing the procedure.

Procedure for channel adjustment of a multi-channel metering apparatus

Multi-channel metering apparatus with automatic calibration, where the individual dispensing channels, the micro-valvesof which are connected with the outlets of a distributororwhose inlet is filled with fluid by a vesselorthus connected, are able to be calibrated in relation to each other in that between the vesselorand the inlet of the distributorora flow sensoris arranged which for calibration during delivery of the fluid via a respective nozzleof a respective dispensing channelrecords the flow and generates signals which are respectively assigned to a defined opening time of a micro-valveand a specific dispensing channeland thus stored allows for individual control of the micro-valvesin order to equalize the tolerances of the dispensing channels

Multi-channel metering apparatus with automatic calibration

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Jena, Germany

Torsten Rausch