Astrazeneca Ab

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Ingemar Starke

Malin Anita Lemurell

Mikael Ulf Johan Dahlstrom

Suzanne Alenfalk

Ann-Margret Lindqvist

Staffan Po Karlsson

David Blomberg

Susanne Alenfalk

Fana Hunegnaw

Mats Peter Nordberg

Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described. 

2-azetidinone derivatives and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia

Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described 

Diphenylazetidinone derivatives for treating disorders of the lipid metabolism

The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Process for their manufacture and pharmaceutical compositions containing them are also described 

Peptides derivatives comprising thiazepine group for the treatment of hyperlipidemic conditions

The present invention relates to compounds of formula (I) wherein R, R, R, R, R, M, R, v, R, R, Rand Rare as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described. 

Benzothiazepine and benzothiazepine derivatives with ileal bile acid transport (IBAT) inhibotory activity for the treatment hyperlipidaemia

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Molndal, Sweden

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