P Tech, LLC

Axiosonic, LLC

Tonya M Bierman

Peter M Bonutti

Justin E Beyers

Bryce G Rutter

Matthew J Cremens

Melvin Joshua Leedle

An electrical stimulation device for modulating a blood-brain barrier (BBB) of a subject includes at least one electrode configured to delivery electrical stimulation to the subject to stimulate a sphenopalatine ganglion (SPG) of the subject, and a control unit in communication with the at least one electrode. The control unit generates a first electrical stimulation signal to the at least one electrode to apply a first electrical stimulation to the subject to stimulate a sphenopalatine ganglion (SPG) of the subject thereby increasing porosity of the BBB from an initial porosity to an increased porosity, and generate, after said first electrical stimulation signal, a second electrical stimulation signal to the at least one electrode to apply a second electrical stimulation to the subject to stimulate the SPG of the subject thereby decreasing porosity of the BBB from the increased porosity to a decreased porosity that is less than the increased porosity.

System and method for affecting porosity of tissue barriers, including blood brain barrier

Optimizing and/or personalizing activities to a user through artificial intelligence and/or virtual reality.

Artificial intelligence and/or virtual reality for activity optimization/personalization

Systems and methods for use in capturing energy from natural resources. In one form, the systems and methods capture energy from natural resources, such as movement of fluid in a body of water, and convert it into electrical energy.

Systems and methods for energy harvest

A disinfecting system includes a housing. An ultraviolet light (UV) source is secured to the housing and configured to emit UV light for disinfection of a target. A processor is secured to the housing in communication with the UV light source. The processor is configured to activate the UV light source for a selected amount of time suitable for disinfection of the target.

Systems and methods for disinfection

An iontophoresis system includes a preloaded reservoir containing one or more doses of a therapeutic agent. As a result, the therapeutic agent does not have to be loaded into the reservoir prior to use. In such a system, the preloaded reservoir is generally disposable. Various components of the iontophoresis system can be combined with the reservoir in a disposable cartridge that is selectively connectable to other, reusable components of the iontophoresis system. In addition, the entire iontophoresis system can be formed from one or more disposable, one-time-use modules.

Systems and methods for delivery of therapeutic agents

The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E.

Systems and methods for thrombosis prevention

A linear generator includes one or more helices, and one or more magnet members movable relative to a first helix to generate electric energy within the first helix. The first helix includes a first coil. The first helix and/or the magnet members have a density less than that of water such that the first helix and/or the magnet members have buoyant properties when the linear generator is at least partially submerged in the water.

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Dieterich, IL, United States of America

Tonya M Bierman