Agilent Technologies, Inc.

Roche Diagnostics Operations, Inc.

Tony Ziegler

Manfred Berndt

Joachim-Richard Wagner

Clemens Plachetka

Thomas Ortmann

Darijo Zeko

Herbert Harttig

Carlo S Effenhauser

Konstantin Shoykhet

Stefan Falk-Jordan

A degasser for at least partially degassing a gas-containing liquid, in particular for a sample separation device, includes a liquid accommodation volume for accommodating the gas-containing liquid during degassing, a negative pressure chamber in which a negative pressure, compared to the liquid accommodation volume, is to be generated, a gas permeable membrane separating the liquid accommodation volume from the negative pressure chamber and arranged so that ultrasound forces at least part of gas of the gas-containing liquid to move through the membrane by a combination of the negative pressure and the ultrasound, and an ultrasound source including an electroactive material and configured for generating ultrasound for actuating the gas-containing liquid and/or the gas permeable membrane.

Vacuum degassing using electroactive material

A fluidic valve includes a valve seat, a valve sealing body placeable at the valve seat when the fluidic valve is closed and being displaced with respect to the valve seat when the fluidic valve is open, a force transmission element coupled with the valve sealing body, and an actuator mechanism configured for actuating the force transmission element for triggering the valve sealing body to carry out an additional movement different from an opening movement and a closing movement of the valve sealing body.

Fluidic valve supporting additional movement in addition to opening and closing movement

A fluid supply device for providing a mobile phase for a sample separating device includes, a supply conduit for providing a fluid which forms at least a part of the mobile phase, a fluid valve which is fluidically coupled with the supply conduit and, depending on its switching state, enables or prevents a passing of the fluid from the supply conduit, an elastic buffer unit which is fluidically coupled upstream of the fluid valve with the supply conduit and which is configured for buffering the fluid, and a fluid conveying unit for conveying the fluid which passes the fluid valve.

Fluid supply devices and fluid member for forming a mobile phase for a sample separating device

A microfluidic component for a sample separation apparatus includes a component body including ceramic and at least one microfluidic structure in the component body. The component body is manufactured by additive manufacturing, in particular by three-dimensional printing.

Manufacture of a microfluidic component by additive manufacturing

A fluid valve for a sample separation apparatus includes a first valve component and a second valve component, which are adjacent to one another and movable relative to one another. The valve components are configured such that, in at least one switching state, at least one switchable fluid channel is formed between the valve components, and at least one part of a surface of at least one of the first valve component and the second valve component is provided with a coating containing gold and/or platinum.

Fluid valve having a coating containing gold and/or platinum

A fluidic valve for switching between different fluid coupling states includes a stator having at least one fluidic stator interface, a rotor having at least one fluidic rotor interface, wherein the rotor is rotatable relative to the stator to thereby switch the fluidic valve between a plurality of different fluid coupling states between the at least one fluidic stator interface and the at least one fluidic rotor interface, and a force transmission mechanism configured for pressing the stator and the rotor together by a contactless force transmission to provide for a fluid tight sealing between the stator and the rotor.

Fluidic valve with contactless force transmission for pressing together stator and rotor

An electrostatic discharge protected device for conducting a fluid through at least one lumen includes a tubing having a hollow interior defining the at least one lumen. The tubing includes an electrically conductive section configured for conducting electric charge, generated within the at least one lumen when the fluid flows through the at least one lumen, away from the at least one lumen.

ESD protected tubing for removing charge from lumen

The invention discloses a micropump having heating elements in which an essentially pulsed operation of the heating elements occurs by means of a control unit. The pulsed operation of the heating elements enables an exact control of the flow rate. With the aid of the control unit it is possible to keep the flow rate constant over a long period of days or to change the flow rate rapidly and precisely.

Growing community of inventors

Steinfeld, Germany

Tony Ziegler