Other

Baxter International Inc.

Baxter Healthcare Sa

Lightship Medical Limited

Tony James

Nicholas Paul Barwell

Michael L Bell

Susumu Arimori

The present invention provides a glucose sensor having a glucose receptor containing a binding site of formula (I): wherein X, n, m and Rare defined herein. Also provided is a glucose sensor molecule for use in such a glucose sensor, the glucose sensor molecule containing the binding site of formula (I). The binding site has been found to have particularly good selectivity for glucose.

Glucose sensor molecule

The present invention provides a glucose sensor having a glucose receptor containing a binding site of formula (I): wherein X, n, m and Rare defined herein. Also provided is a glucose sensor molecule for use in such a glucose sensor, the glucose sensor molecule containing the binding site of formula (I). The binding site has been found to have particularly good selectivity for glucose. 

Glucose sensor molecules

An analytical system for detecting a saccharide is provided. The analytical system includes a saccharide sensor attached to a solid substrate and having the formula: Where Z is selected from the group consisting of hydrogen, alkyl groups, an aryl; N is a nitrogen atom; Band Bare independently selected binding groups, wherein the binding groups are capable of binding an saccharide; Sp is a spacer; An is an anchor group for attaching the sensor to solid substrate, including a bead; and n=1 or 2, m=1 or 2, y=1 or 2, and p is an integer. In one embodiment the saccharide sensor preferentially detects glucose. The invention further provides beads having the saccharide sensor attached thereto and methods of detecting glucose using the system.

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Bath, United Kingdom

Tony James