Editas Medicine, Inc.

Tongyao Wang

Hariharan Jayaram

John Zuris

Jennifer Leah Gori

Gordon Grant Welstead

Christopher Borges

Penrose Odonnell

Penrose O'donnell

CRISPR/Cpf1-related compositions and methods for treatment of cancer.

Crispr-CPF1-related methods, compositions and components for cancer immunotherapy

Disclosed herein are compositions and methods for increasing the immunocompatibility of donor cells (e.g., HSCs or T-cells) for transplantation to a recipient subject, as well as database schemes for use in the methods. The methods and compositions described herein result in the allele-specific modification of one or more immunogenicity genes (e.g., an HLA gene) of a cell, resulting in cells that are suitable for transplantation into a recipient subject.

CRISPR/Cas-related methods and compositions for improving transplantation

Growing community of inventors

Malden, MA, United States of America

Tongyao Wang