Hangzhou Zero Zero Technology Co., Ltd.

Dartmouth College

Beigene, Ltd.

Sony Corporation

Beigene Switzerland Gmbh

Zero Zero Robotics Inc

Beijing Zero Zero Infinity Technology Co., Ltd

Tsinghua University

Boe Technology Group Co., Ltd.

Hewlett Packard Enterprise Development LP

Chengdu Boe Optoelectronics Technology Co., Ltd.

Baidu Online Network Technology (beijing) Co., Ltd.

Hangzhou Zero Zro Technology Co., Ltd.

Hanzhou Zero Zero Technology Co., Ltd.

Tong Zhang

Mengqiu Wang

Kang Li

Lixin Liu

Zhaozhe Wang

Jia Lu

Jing Song

Charles L Sentman

Qi Liu

Pengxiang Jin

Hao Peng

Qimei Cui

Min Wei

Zheng Qu

Lanlan Xu

Qinyan Jiang

Lei Zhang

Wei Sun

Weijuan Gao

Guanqun Zhang

Hui Liang

Lai Wang

Lusong Luo

Zhongbin Qin

Changyou Zhou

Liu Xue

Xian Su

Zhiyu Tang

Hanqing Guo

Wei Li

Jing Li

Guoliang Zhang

Yucheng Li

Jingming Liu

Sixue Li

LaiJun Chen

Shengwei Mei

Qiang Lu

XiaoDai Xue

Chenhui Qian

Mengwen Tan

Qicheng Li

Yusen Qin

Zhiying Ren

Yanshen Kang

Xuyang Zhang

Shuang Gong

Yalin Zhang

Jinglong Wang

Xuelin Zhang

Tianwen Zheng

Yi Zhang

Chen Sun

Xin Guo

Hui Wang

Ming Hu

Ye Liu

Wei He

Yang Zhou

Shun Zhang

Haijun Qiu

Chang Luo

Jinhui Chen

Zhiwei Wang

Yuanqi Zhang

Zhidong Wang

Hongwei Ma

Taofeng Xie

Youngyik Ko

Ping Wen

Nan Hu

Yang Zeng

Yanzhao Hou

Haoyuan Fan

Yunhang Guo

Xinghua Li

Qun Ma

Hexiang Wang

Tianci Chen

Bo Ren

Xiaoyan Yang

Tianyi Wang

Xiping Li

Haishan Wu

Long Zhang

Fan Yang

Jinhwan Hwang

Yuanfu Chen

Xi Zhang

Menqiu Wang

Weiqi Liu

Xiaonan Cheng

Shanshan Bu

Jin Li

Guofan Wu

Jianye Liu

Jiaxin Ma

The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.

Chimeric NK receptor and methods for treating cancer

Provided are antibodies that specifically bind to TIGIT (T cell immunoreceptor with Ig and ITIM domains, WUCAM or Vstm3) and inhibit Tigit-mediated cellular signaling and activities in immune cells. The anti-TIGIT antibodies can be used to treat or diagnose cancer, infectious diseases or other pathological disorders that may be modulated by Tigit-mediated functions.

Anti-TIGIT antibodies and their use as therapeutics and diagnostics

A display panel, including an active area and a peripheral area, which is located outside of the active area, wherein the active area comprises a base substrate, and a display structure layer and a touch structure layer sequentially arranged on the base substrate; the peripheral area includes an isolation dam, a first ground trace and a second ground trace arranged on the base substrate; and the first ground trace is located at a side of the isolation dam close to the active area, and the second ground trace is located at a side of the isolation dam away from the active area.

Display panel and display touch-control apparatus

The present disclosure provides antibodies and antigen-binding fragments thereof that bind to human OX40 (ACT35, CD134, or TNFRSF4), a pharmaceutical composition comprising said antibody, and use of the antibody or the composition for treating a disease, such as cancer. In particular, the anti-OX40 antibody of the present invention does not interfere with the binding of OX40-ligand to its receptor.

Anti-OX40 antibodies and methods of use

Implementations of the present disclosure relate to intrusion detection information. A method comprises detecting, by an access point (AP), at least one device in a wireless communication network to be an illegal device. The method also comprises obtaining, by the AP, intrusion detection information related to the at least one device, the intrusion detection information comprising at least one identifier of the at least one device.

Broadcast of intrusion detection information

An aerial device includes a body, an optical system having gimbal supporting a camera, a lift mechanism coupled to the body, a haptic sensor coupled to the body and configured to generate haptic data, and a processing system disposed in the body and in data communication with the haptic sensor. The processing system is configured to process the haptic data to understand an intended position of the aerial device and/or an intended orientation of the gimbal and convert the intended position to a target position of the aerial device and/or the intended orientation to a target orientation of the gimbal utilizing said processed data irrespective of an initial position of said aerial device and an initial orientation of said gimbal. Also disclosed is a method for controlling the aerial device.

Aerial device and method for controlling the aerial device

Antibodies, chimeric antigen receptors, and bispecific T-cell engagers having specificity for B7-H6 and methods for using the same in the diagnosis and treatment of disorders associated with B7-H6 expression are provided.

Anti-B7-H6 antibody, fusion proteins, and methods of using the same

The present disclosure provides an aerial system, comprising: a body; a lift mechanism coupled to the body; an optical system coupled to the body; and a computer system having at least one processor and at least one memory comprising first program instructions. When the first program instructions are executed by the at least one processor, the at least one processor may be configured to: receive a target operation, the target operation associated with a flight trajectory and a predefined action performed by the optical system and execute the target operation.

System and method for providing easy-to-use release and auto-positioning for drone applications

Nucleic acid constructs encoding chimeric NK receptor, cells containing, and therapeutic use thereof

The present disclosure provides an unmanned flight system and a control system for an unmanned flight system. The unmanned flight system comprises: a body and a lift mechanism connected to the body, wherein the lift mechanism includes two rotor assembly arm structures respectively provided on two sides of the body, wherein each of the rotor assembly arm structures respectively includes: an arm, a pivotable rotor assembly, a motor for driving the rotor assembly to pivot about a pivot axis, and a motor base for mounting the motor, wherein one end of the arm is pivotally connected to one side of the body, the motor base is pivotally provided on the other end of the arm, and a rotational axis of the motor base is higher than a center of gravity of the unmanned flight system. The unmanned flight system according to the present disclosure can achieve a longer flight time, a simple rotor assembly structure, and easier overall assembly and maintenance.

Unmanned flight systems and control systems thereof

Disclosed herein is a method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a targeted therapy agent. Also, disclosed a pharmaceutical combination comprising a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor, or a targeted therapy agent and the use thereof.

Treatment of B cell cancers using a combination comprising Btk inhibitors

Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) and inhibit PD1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD1-mediated functions.

Anti-PD1 antibodies and their use as therapeutics and diagnostics

An aerial system, including a processing system, an optical system, an actuation system and a lift mechanism, includes an autonomous photography and/or videography system, implemented, at least in part, by the processing system, the optical system, the actuation systemand the lift mechanism. The autonomous photograph and/or videography system performs the steps of establishing a desired flight trajectory, detecting a target, controlling the flight of the aerial system as a function of the desired flight trajectory relative to the target using the lift mechanism and controlling the camera to capture pictures and/or video.

System and method for providing autonomous photography and videography

An unmanned aerial system includes a remote controller device and an unmanned aerial vehicle. A user input on the remote controller device indicates a flight command requested by a user. The remote controller device determines a current position and/or orientation of the remote controller device in response to the flight command from the user. The current position and/or orientation is sent to the vehicle. The vehicle responsively determines a desired orientation of the unmanned aerial vehicle as a function of the current position and/or orientation of the remote controller device and operates a lift mechanism to execute a flight operation based on the desired orientation of the unmanned aerial vehicle and the current position of the remote controller device.

One-handed remote-control device for aerial system

The present disclosure relates to the field of energy storage, and provides a rapid-response energy storage system and a using method thereof. The system comprises an air storage chamber, a compressor unit, an expander unit, a compressor unit lubrication station, an expander unit lubrication station, a compressor unit oil cooler, an expander unit oil cooler, a compressor unit oil pump and an expander unit oil pump; an outlet of the compressor unit communicates with an inlet of the air storage chamber through a heating pipe inside the expander unit lubrication station, and an outlet of the air storage chamber communicates with a heating pipe inside the compressor unit lubrication station sequentially through a regulating valve and the expander unit; the compressor unit lubrication station, the compressor unit oil pump, an oil way inside the compressor unit and the high-temperature side of the compressor unit oil cooler are sequentially connected end to end to form a first oil circulation loop; and the expander unit lubrication station, the expander unit oil pump, an oil way inside the expander unit and the high-temperature side of the expander unit oil cooler are sequentially connected end to end to form a second oil circulation loop. According to the present disclosure, rapid responses can be achieved and the lubricating oil can be heated without the consumption of external thermal energy.

Rapid-response compressed air energy storage system and using method thereof

Growing community of inventors

Beijing, China

Tong Zhang