Avago Technologies Ecbu IP (Singapore) Pte. Ltd.

Alverix, Inc.

Agilent Technologies, Inc.

Avago Technologies General IP (Singapore) Pte. Ltd.

Avago Technologies Ecbu IP Pte. Ltd.

Becton Dickinson and Company Limited

Other

Pixart Imaging Incorporated

Tong Xie

Marshall Thomas DePue

Stephan Hengstler

Vincent C Moyer

Douglas Michael Baney

Michael John Brosnan

Benny Wing Hung Lai

Mark Melvin Butterworth

Ramakrishna Kakarala

Roopinder Singh Grewal

Marshall T Depue

Dale W Schroeder

Timothy James Orsley

Akihiro Machida

Ralph Henry Page

Paul Michael Welch

Yakov Sidorin

Falgun Patel

Marshall Thomas Depue

George Edward Smith

Gregory Douglas VanWiggeren

Susan Hunter

Lye Hock Bernard Chan

Tong Sen Liew

David Charles Feldmeier

Scott Dylewski

Tiong Heng Siah

William Bilobran

Certain aspects relate to systems and usage techniques for modular lateral flow assay reader devices that can receive a number of different modules having a barcode scanning input device and optional network connectivity capabilities. A barcode scanning module can provide a simple input method that reduces errors compared to manual data entry. A network connectivity module can enable transmission of test results over a public network for standardizing, tracking and electronically connecting test results from assay reader devices located throughout a network. Such devices can programmatically implement a simplified workflow whereby pressing a single button readies the device for imaging, analyzing, and data storage/transmission and, in some implementations, configures the device to operate in one of a plurality of device operation modes.

Modular assay reader device

A system is disclosed in which a plurality of in-vitro diagnostic (IVD) devices each include a network communication device for connecting to a publicly accessible data network. For example, IVD devices are provided with a cellular modem for connecting to a public cellular network. These IVD devices connect to the data network upon completion of a diagnostic test, and upload results of the test, as well as other appropriate data, to a remote device which is also on the network. The IVD devices also download appropriate data from remote network elements. The remote network element may be a network element such as a Hospital Information System (HIS) or Laboratory Information System (LIS) database. Alternatively, the remote device may be a remote server or another IVD device. This connectivity enables the system to accumulate diagnostic test data, and to analyze, report, and/or update the IVD devices based on the accumulated data.

Distributed network of in-vitro diagnostic devices

Low-cost assay test strip readers are disclosed. Such readers enable creation of profiles of analyte reactions detected on an assay test strip utilizing a simple detector fixedly mounted to a body of the reader. The detector may be a single detector, such as a photodetector, which detects an optical signal at a single point. The assay test strip is inserted and/or removed from the test strip reader and the detector detects the optical elements of the strip during such insertion and/or removal. The movement of the test strip with respect to the body enables the detector to scan a length of the test strip, such that a one-dimensional profile of the optical signals can be generated. The reader may convert the detected profile into a displayable indication of analyte concentrations for diagnostic purposes. Moving the test strip relative to an array of detectors enables creation of a two-dimensional profile.

Assay reader operable to scan a test strip

A system and method for augmenting or adding to the information used by an in-vitro diagnostic or other diagnostic device to generate results of a test is disclosed. A diagnostic device is capable of generating test results based on a sample, such as a sample provided by a patient, and is also capable of receiving additional information to enhance the results providable by the device. For example, an in-vitro diagnostic device is configured to read a lateral flow assay test, and is configured to receive additional diagnostic, network, test identification, or environmental information over a network. Using both the result of the diagnostic test and the additional information, the disclosed device provides more thorough, accurate, and reliable diagnostic information. The results generated by the device may be communicated to an appropriate remote device to enhance the results obtainable by such tests.

Lateral flow assay testing device using external information in conjunction with test results

In-vitro diagnostic device using external information in conjunction with test results

Low-cost assay test strip readers enable creation of profiles of analyte reactions detected on an assay test strip utilizing a simple detector fixedly mounted to a body of the reader. The detector may be a single detector, such as a photodetector, which detects an optical signal at a single point. The assay test strip is inserted and/or removed from the test strip reader and the detector detects the optical elements of the strip during such insertion and/or removal. The movement of the test strip with respect to the body enables the detector to scan a length of the test strip, thereby generating a profile of optical signals representing analyte reactions along a one-dimensional portion of the test strip. The reader may convert the detected profile into a displayable indication of analyte concentrations for diagnostic purposes.

An optical input card is shaped and sized for removable slidable insertion within a slot of a portable computer. The optical input card comprises an optical navigation sensor, a control panel and a wireless communication module. The optical navigation sensor is disposed on the first side of the card for exposure to a navigation surface and is configured to capture a first user control input. The control panel on a second side of the card is configured to capture at least one second user control input. The wireless communication module is configured to wirelessly communicate the first user control input and the at least one second user control input to the portable computer.

User control input device

A contaminant-neutralizing cradle comprises a base and a support surface configured to removably receive a coherently-illuminated mouse. A neutralizing element is disposed on the support surface for alignment with at least one exposed surface of an optics module of the mouse and is configured to neutralize the optical effect of a contaminant on the at least one exposed surface. A method of neutralizing contaminants for an optical mouse comprises providing a mouse containing an optics module having at least one surface exposed to an opening of the mouse and interposing a barrier in the mouse between a contaminant and the at least one exposed surface. A method of detecting contaminants comprises aligning an optics module of a mouse with an imaging surface, obtaining a first image of the imaging surface, via application of coherent illumination from the optics module to the imaging surface, analyzing the first image to identify an interference pattern associated with a contaminant, alerting a user if a parameter of the interference pattern exceeds a threshold value.

Contaminant-resistant optical mouse and cradle

Growing community of inventors

San Jose, CA, United States of America

Tong Xie