Bio-rad Laboratories, Inc.

Tong Le

Robert K Likuski

Anthony F Prestigiacomo

Donald J Bartling

Kurt D Kramer

Don Bartling

Yao Kunquan

Kent Matsumoto

Methods and systems for analyzing ratios of analytes within a flowing sample are provided. The flowing sample can be processed in real-time to determine a time interval over which a predetermined amount of a group of analytes passes by a fixed point in a flow cell. The predetermined amount can be routed to a sample container for future processing. The sample can comprise diluted blood and the analytes can comprise a component of hemoglobin, such as A1c, and the total amount of hemoglobin, of which the predetermined amount is metered.

Measuring multi-analyte samples using an in-line flow cell

An automated analyzer for biological samples that contain particulate matter is adapted to be able to process a large number of samples without changing the analytical cartridge, and in many cases without changing the internal switching valves, by including a filter in the low-pressure section of the analyzer, and preferably configuring the analyzer to be able to perform backflushing on the filter between sample injections.

Automated analyzer with low-pressure in-line filtration

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Pinole, CA, United States of America

Tong Le