Xiamen University

Rutgers, the State University of New Jersey

Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Yang Sheng Tang Company Limited

University of Medicine and Dentistry of New Jersey

Tong Cheng

Ningshao Xia

Xiangzhong Ye

Jun Zhang

Hua Zhu

Yimin Li

Wei Wang

Junkai Wan

Shuai Yue

Ji Miao

Tao Zhang

Yali Zhang

Longfa Xu

Wenkun Fu

Provided are an enterovirus D68 (EV-D68) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the EV-D68 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, or a pharmaceutical composition comprising the EV-D68 or a modified form thereof, or the nucleic acid molecule, and use of the EV-D68 or a modified form thereof, or the nucleic acid molecule in the manufacture of a pharmaceutical composition for treating a tumor.

Virus for treatment of tumor

Provided are use of an Echovirus 25 (ECHO25) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the ECHO25 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, in treatment of a tumor in a subject, and in the manufacture of a medicament for treatment a tumor in a subject.

Echovirus for treatment of tumors

Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.

ORF7 deficient varicella virus, vaccine comprising the virus and use thereof

The RNAi target sequences, which could be used for treating AIDS through targeting HIV. Based on the target sequences, recombinant expression vectors, packaging vectors and cells were constructed, which express siRNA and/or miRNA and/or ribozyme and/or antisense oligonucleotide for targeting HIV. And the applications of said recombinant expression vectors, packaging vectors and cells in preparing medicament for treating AIDS.

RNA interference target for treating AIDS

Growing community of inventors

Province, China

Tong Cheng