Sony Corporation

Sony Group Corporation

Tomoyuki Umetsu

Masahiro Matsumoto

Kenji Tanaka

Kenji Yamane

Masaaki Hara

Naoki Ide

Nobuhiro Hayashi

Yoichi Katsumoto

Yasunobu Kato

Yoshiki Okamoto

Yoshihito Hayashi

Shin Masuhara

Marcaurele Brun

Shinji Omori

Kazumasa Sato

Shiori Oshima

Koji Futamura

Seungmin Lee

There is provided a technology for improving analysis accuracy and sorting accuracy in a technology for analyzing and sorting particles. In the present technology, there is provided a particle analyzer including: a vibration unit that applies vibration to a fluid including a sample flow which contains a particle and a sheath flow which flows so as to include the sample flow to form a droplet in the fluid; a charging unit that applies electric charge to the droplet including the particle; a side stream imaging unit that images a state of the droplet deflected by the electric charge; and a charging control unit that controls a timing of charging on the basis of an image captured by the side stream imaging unit.

Particle analyzer and particle analysis method

A measurement spectrum obtained by irradiating a particle labeled with a plurality of fluorescent dyes with excitation light is separated for each fluorescent dye with high accuracy. Provided is a particle analysis system () including a plurality of photodetectors () configured to acquire light generated by irradiating a particle labeled with a plurality of fluorescent dyes with excitation light; and an information processing unit () configured to calculate fluorescence intensity of each fluorescent dye by performing separation processing on a measurement spectrum based on measured values from the plurality of photodetectors () with a single staining spectrum of each fluorescent dye, in which the separation processing is performed by using a weighted least squares method (WLSM) including a weight determined based on a variation in the measured values.

Particle analysis system and particle analysis method

A microparticle measurement spectrometer includes a spectroscopic element that disperses light emitted from microparticles flowing through a flow path, and a photoelectric conversion array that has a plurality of light receiving elements having different detection wavelength ranges and converts optical information obtained by the light receiving elements into electrical information, in which the photoelectric conversion array has a uniform output of all channels when light with which the amount of light per unit wavelength becomes same is incident.

Microparticle measurement spectrometer, microparticle measurement device using the microparticle measurement spectrometer, and method for calibrating microparticle measurement photoelectric conversion system

To provide a cell evaluation device capable of evaluating cells and a secretory substance emitted from the cells accurately and precisely. Provided is a cell evaluation device including a first capturing unit that captures a secretory substance secreted by cells, and an image acquisition unit that acquires an image obtained by imaging observation light of the cells and light emitted from a luminescent substance bonded to the secretory substance, in which the image acquisition unit and the first capturing unit are disposed in this order, and the image acquisition unit acquires position information for the cells and the secretory substance.

Cell evaluation device and cell evaluation system

To provide a technique capable of handling quantitative data in a spectrum type microparticle measurement device without causing deterioration of the SNR. The present technology provides a microparticle measurement spectrometer including a spectroscopic element that disperses light emitted from microparticles flowing through a flow path, and a photoelectric conversion array that has a plurality of light receiving elements having different detection wavelength ranges and converts optical information obtained by the light receiving elements into electrical information, in which the photoelectric conversion array has a uniform output of all channels when light with which the amount of light per unit wavelength becomes same is incident.

The fine particle measurement apparatus according to the present technology includes a detection section, a multiplication factor setting section, a correction factor calculation section, and a spectrum generation section. The detection section has a plurality of detectors for detecting light from fine particles. The multiplication factor setting section sets a multiplication factor for each of the plurality of detectors. The correction factor calculation section calculates a correction factor on the basis of the set multiplication factor. The spectrum generation section generates spectral data by correcting a value detected by the detector, with the calculated correction factor.

Fine particle measurement apparatus, information processing apparatus, and information processing method

An information processing device includes a statistical processing unit that performs statistical processing for a group of spectra obtained by applying light to a group of microparticles that exhibit one response property with respect to light, and on a basis of a result of the statistical processing, exclude a spectrum indicating an outlier from the group of spectra, and a reference spectrum calculation unit that calculates a reference spectrum using the group of spectra from which the spectrum indicating the outlier has been excluded.

Information processing device, information processing method, and information processing system

Provided is a cell determination device including a classification unit configured to classify individual cells based on one of a relaxation strength, a relaxation frequency, and low-frequency conductance obtained from a complex dielectric constant spectrum of the cells.

Cell determination device, cell determination system, and cell determination method

Disclosed herein is a dielectric cytometric apparatus capable of analyzing cells and sorting the cells without adopting an optical analysis method and provides a dielectric cytometric cell sorting method for the apparatus. A stenosis channel allowing a single cell to flow is created on a cell injection section of a micro flow channel device used as a portion of the dielectric cytometric apparatus. A pair of measurement electrodes is created on the stenosis channel and an analyzer connected to the measurement electrodes measures the complex dielectric constant of for every cell passing through the stenosis channel. A electric-field application section provided on the downstream side of the stenosis channel applies an electric field for changing the flow of the cells inside a flow channel on the basis of information on the measured complex dielectric constants so that the cells can be sorted by making use of branch channels.

Dielectric cytometric apparatus and dielectric-cytometric cell sorting method

A terahertz spectrometer includes: a terahertz-wave generating element; an elliptical mirror; an optical lens configured to apply a terahertz wave generated by the terahertz-wave generating element, obliquely to a focusing plane of a first focus of the elliptical mirror; and a terahertz-wave detecting element arranged at a second focus of the elliptical mirror.

Terahertz spectrometer

A probe apparatus includes a first focusing lens and a second focusing lens. The first focusing lens is arranged on a surface of a base to which a terahertz excitation beam is applied, the surface being opposite to the surface to which terahertz excitation beam is applied, with the lens axis deviated from the center of a point at which the terahertz excitation beam is applied. The second focusing lens is arranged on a surface of a base to which a terahertz detected beam is applied from a source of the terahertz excitation beam, the surface being opposite to the surface to which the terahertz detected beam is applied, with the lens axis deviated from the center of a point at which the terahertz detected beam is applied, in a direction opposite to the direction in which the lens axis of the first focusing lens is deviated.

Growing community of inventors

Tokyo, Japan

Tomoyuki Umetsu