Toray Industries, Inc.

Tomoya Miyoshi

Naoki Izumimoto

Katsuhiko Iseki

Yasuhiro Morita

Shunsuke Iwano

Shuji Udagawa

Yuji Osada

Kei Takahashi

Motohiro Shiraki

Tetsuro Koreeda

Masanori Murakami

Keiyu Oshida

Eriko Higashi

A cyclic amine derivative represented by a general formula (I) or a pharmacologically acceptable salt thereof: wherein n represents 1 or 3, Rrepresents an alkyl group having 1 to 6 carbon atoms unsubstituted, substituted with a halogen atom or substituted with an alkyloxy group having 1 to 4 carbon atoms and Rrepresents a hydrogen atom or a halogen atom.

Cyclic amine derivative and pharmaceutical use thereof

A compound exerts a strong analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. A cyclic amine derivative represented by general formula or a pharmacologically acceptable salt thereof:  A method of treating neuropathic pain includes administering a therapeutically effective amount of the cyclic amine derivative to a mammal. A method of treating fibromyalgia syndrome includes administering a therapeutically effective amount of the cyclic amine derivative to a mammal.

A compound exerts a strong analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. The cyclic amine derivative is represented by formula, a prodrug thereof or a pharmacologically acceptable salt thereof: wherein A represents a group represented by Formula (IIa), (IIb) or (IIc): wherein

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Kamakura, Japan

Tomoya Miyoshi