Ito En, Ltd.

Tomonori Unno

Takami Kakuda

Ayumu Nozawa

Iwao Sakane

Yuko Suzuki

Teruo Miyazawa

Kiyotaka Nakagawa

A beverage is prepared, which is a beverage containing catechins in ester form (A, mg/L), catechins in free form (B, mg/L), and caffeine (C, mg/L), the contents thereof being()=500 to 6000 mg/L&#x2003;&#x2003;(1)()/()=0.7 to 1.0&#x2003;&#x2003;(2)()/()=6 to 27,&#x2003;&#x2003;(3)such that a high concentration of catechins with high biological functionality, improved flavor and improved product quality with low occurrence of sediment is maintained.

Beverage comprising cathechins and caffeine

In order to provide a xanthine oxidase inhibitor having as an effective component an extract from highly safe plants, ten kinds of plant materials were compared for the xanthine oxidase inhibition activity, and in consequence (banaba) was found to have the strongest activity. In addition, it was found that the xanthine oxidase inhibition activity was present in an &ldquo;crude extract&rdquo; obtained by extracting banaba with hot water or the like, &ldquo;resin adsorbed components&rdquo; obtained by adsorbing the crude extract on a styrene-divinyl benzene synthetic resin or the like, and &ldquo;organic solvent soluble components&rdquo; obtained by the partition of the resin adsorbed component between water and an organic solvent. Among them, the &ldquo;organic solvent soluble components&rdquo; described above were purified with high performance liquid chromatography to obtain &ldquo;ellagic acid,&rdquo; an &ldquo;ellagic acid derivative,&rdquo; an &ldquo;ellagic acid analog compound&rdquo; and a &ldquo;lignan,&rdquo; which were found to have a more superior xanthine oxidase inhibitor activity. The present invention provides a xanthine oxidase inhibitor having each of these extracted materials as an effective component.

Xanthine oxidase inhibitor and method for producing the same

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Shizuoka, Japan

Tomonori Unno