Ajinomoto Co., Ltd.

Tomomi Yoshida

Manabu Kitazawa

Sho Senda

Yoko Kuriyama

Satoru Okamoto

Nao Sugimoto

Ikue Harata

Daisuke Ejima

Tadakiyo Nakagawa

Munetaka Tokumasu

Masayo Date

Sen Takeshita

Kaori Kobayashi

Kayo Matsumoto

Haruna Sato

Hiroki Inoue

Yumi Ando

Takayoshi Fujii

Culture media, which contain albumin carrying a reduced amount of fatty acid, are useful for culturing stem cells.

Medium for culturing stem cells

Cultivating a pluripotent stem cell in a medium comprising at least one member selected from the group consisting of ethanolamine, an ethanolamine analog, and a pharmaceutically acceptable salt thereof, and which is substantially free of &#x3b2;-mercaptoethanol or contains &#x3b2;-mercaptoethanol at a concentration of not more than 9 &#x3bc;M, and the like, is effective for the proliferation of a pluripotent stem cell while maintaining an undifferentiated state.

Culture method for stable proliferation of pluripotent stem cell while maintaining undifferentiated state

Provided is a compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof. This novel compound has a glycogen-synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe.  In the formula, Ar is an aromatic carbocyclic ring or a heterocyclic ring; and Aris represented by any one of the following rings and the like. 

Pharmaceutical composition for treating diabetes

Growing community of inventors

Kawasaki, Japan

Tomomi Yoshida