Tohoku University

Japan Aviation Electronics Industry, Limited

Kureha Kagaku Kogyo Kabushiki Kaisha

Unitika Ltd.

Mochida Pharmaceutical Co., Ltd.

Seikagaku Corporation

Daiichi Pure Chemicals Co., Ltd.

Azul Energy Inc.

Tomokazu Matsue

Atsushi Suda

Ryota Kunikata

Kosuke Ino

Kumi Inoue

Hitoshi Shiku

Hiroyuki Hayashi

Tatsuo Kimura

Mayuko Terauchi

Noriko Taira

Isamu Uchida

Takahiro Ito

Yusuke Kanno

Takashi Yamauchi

Hiroshi Yabu

Toshio Oda

Matsuhiko Nishizawa

Hiroshi Yamada

Hikaru Mizumura

Masamichi Fujihira

Tetsuo Osa

Hiroya Abe

Noboru Fukasaku

Kentaro Ito

Jun-ichi Kosuge

Miho Ikegawa

Hsien-Chang Chang

Akinori Ueno

Akichika Kumatani

Kohei Nozaki

Yutaro Hirai

Provided is a method for electrochemically detecting a catalytic reaction product that is generated by progress of a catalytic reaction in a first lump of liquid and dissolved in the first lump of liquid, the method including: containing the first lump of liquid and a second lump of liquid in a liquid bath, the second lump of liquid being in contact with the first lump of liquid to form a liquid-liquid interface and not dissolving the catalytic reaction product; arranging a working electrode in the first lump of liquid, and arranging a counter electrode and a reference electrode in the second lump of liquid; and detecting a current flowing through the working electrode by an oxidation or reduction reaction of the catalytic reaction product at the working electrode.

Electrochemical detection method for catalytic reaction product, and transducer

An electrochemical measurement apparatus includes: a tank containing electrolytic solution and a sample that generates or consumes measurement target substances in the electrolytic solution; a plurality of uniformly mixed working electrodes; and a counter electrode; the apparatus adapted to simultaneously apply a voltage between each of the working electrodes and the counter electrode; and the apparatus configured to measure a current that flows between each of the working electrodes and the counter electrode; wherein any two working electrode groups are mutually different in at least any of the determined voltage, presence/absence of a molecular modification of an electrode surface, and a species of the molecular modification; and whereby a distribution in measurement area of the currents that flow through the working electrodes is acquired.

Electrochemical imaging method

Electrochemical measurement apparatus and transducer

A hydrogel is formed by a reaction which is induced, in an electrolytic solution, by an electrode product electrochemically generated by electrodes installed in the electrolytic solution. An apparatus including an electrolytic tank with a bottom surface on which a two-dimensional array of working electrodes is provided and a counter electrode installed in the electrolytic tank is prepared. An electrolytic solution containing a dissolved substance that causes electrolytic deposition of a hydrogel is housed in the electrolytic tank. By applying a predetermined voltage to one or more selected working electrodes of the two-dimensional array, a hydrogel with a two-dimensional pattern corresponding to the arrangement of the selected working electrodes is formed.

Method of electrochemically producing hydrogel, method of producing hydrogel with pattern formed of cells, hydrogel production apparatus, and transducer

An electrochemical measurement method is provided in which a working electrode that causes an oxidation-reduction reaction with a measurement target and a counter electrode connected to the working electrode are provided in an electrolytic solution containing the measurement target, and a measuring voltage is applied between the working electrode and the counter electrode to measure a current that flows between the working electrode and the counter electrode in proportion to the amount of the measurement target, wherein an eliminating electrode is provided in the electrolytic solution, and the method performs: eliminating the measurement target by applying an eliminating voltage, which has the same polarity as the measuring voltage, between the eliminating electrode and the counter electrode to oxidize or reduce the measurement target; diffusing a new measurement target; and measuring the current by applying the measuring voltage between the working electrode and the counter electrode.

Electrochemical measurement method, electrochemical measurement device and transducer

An electrochemical measurement device for measuring a chemical substance generated or consumed in a biological sample in a solution includes electrode surfaces, a spacer, and at least one wall plate. The electrode surfaces, the spacer, and the wall plate are arranged on the same flat surface. Each of the electrode surfaces has a diameter dnot more than 80 μm. A height of the spacer has a predetermined value within a range given by h=21.8(d+0.8)/(d+9.7)±5 [μm]. The spacer has a structure in which an enclosed three-dimensional region is not formed by the biological sample, the flat surface, and the spacer while the biological sample is in contact with the spacer. The wall plate has a property of being impervious to a dissolved substance in the solution and has a height not less than the height of the spacer. Two of the electrode surfaces are separated by the wall plate.

Electrochemical measurement device and transducer

The present invention provides a catalyst which has oxygen reduction catalytic ability surpassing that of a platinum-carrying carbon material. This catalyst comprises a carbon material and a metal complex represented by formula (1). In formula (1), Xto Xeach independently represent a hydrogen atom or a halogen atom, Dto Deach represent a nitrogen atom or a carbon atom wherein the carbon atom has bound thereto a hydrogen atom or a halogen atom, and M represents a metallic atom.

Catalyst, liquid composition, electrode, catalyst electrode for electrochemical reaction, fuel cell, and air battery

Provided are a device and a method for rapidly and simply detecting endotoxin without using an expensive reagent. The endotoxin detection device includes: a region containing an electrolyte solution; a partitioning member that partitions the region into two compartments such that the two compartments are in communication via a nanopore; a first electrode that is disposed in a first compartment; a second electrode that is disposed in a second compartment and is electrically connected to the first electrode; an electrolyte solution flow generating means that causes electrolyte solution in the first compartment to move to the second compartment via the nanopore; an application means that applies voltage between the first electrode and the second electrode; and a monitoring means that monitors current.

Endotoxin detection device and endotoxin detection method

An electrochemical measurement device for measuring a chemical substance generated or consumed in a biological sample in a solution includes electrode surfaces, a spacer, and at least one wall plate. The electrode surfaces, the spacer, and the wall plate are arranged on the same flat surface. Each of the electrode surfaces has a diameter dnot more than 80 &#x3bc;m. A height of the spacer has a predetermined value within a range given by h=21.8(+0.8)/(d+9.7)&#xb1;5 [&#x3bc;m]. The spacer has a structure in which an enclosed three-dimensional region is not formed by the biological sample, the flat surface, and the spacer while the biological sample is in contact with the spacer. The wall plate has a property of being impervious to a dissolved substance in the solution and has a height not less than the height of the spacer. Two of the electrode surfaces are separated by the wall plate.

The present invention addresses the problem of providing a means for making highly sensitive and stable measurements possible using electrochemical measurement methods. This problem is resolved by providing: a labeling substance represented by general formula (1) and used to label a substrate; a measurement substrate that is formed by being labeled using the labeling substance; a method of measuring using electrochemical measurement methods that use the measurement substrate; and a reagent kit that includes as components the labeling substance and/or the measurement substrate. (In general formula (1), Ris either H or an alkyl group (CH), m is an integer of 1-4, Ris an alkyl group (CH), and n is an integer of 1-4.)

Electrochemical measurement using phenylenediamine derivative

An electrochemical measurement method is provided in which a working electrode and a counter electrode are provided in an electrolytic solution containing the measurement target and a measuring voltage is applied between the working electrode and the counter electrode to measure a current flowing between the working electrode and the counter electrode in proportion to the amount of the measurement target. A measurement target eliminating thin-wire electrode made of thin wire stretched in such a shape that extends from one point on the bottom into space in the electrolytic solution well and back to another point on the bottom is provided. The electrochemical measurement method includes: eliminating the measurement target by applying an eliminating voltage having the same polarity as the measuring voltage between the measurement target eliminating thin-wire electrode and the counter electrode; and diffusing a new measurement target after stopping the application of the eliminating voltage.

Electrochemical measurement method, electrochemical measurement apparatus and transducer

An electrochemical measurement method for electrochemically measuring a chemical substance generated or consumed in a biological sample in a solution is provided which includes performing measurement by placing the biological sample at a distance away from an electrode surface in the direction perpendicular to the electrode surface. The distance is determined in advance on the basis of simulation in which a current flows through a working electrode.

Growing community of inventors

Sendai, Japan

Tomokazu Matsue