Hitachi-High-Technologies Corporation

Hitachi, Ltd.

Hitachi High-Tech Corporation

Uacj Corporation

Applera Corporation

Denso Corporation

Life Technologies Corporation

Tomohiro Shoji

Ryoji Inaba

Masaya Kojima

Mitsuru Oonuma

Akira Omachi

Shoji Tomida

Kantaro Maruoka

Yasushi Shimizu

Yoshiyuki Okishima

Shuhei Yamamoto

Tomonari Morioka

Daizo Tokinaga

Takashi Gomi

Takeshi Ohura

Muneo Maeshima

Seiichi Ugai

Yoshitaka Kodama

Toshiaki Kita

Masao Fukunaga

Masatoshi Narahara

Takayasu Furukawa

Hirokazu Kato

Kiyoshi Tsukada

Akihiro Suzuki

Manabu Akiba

Shozo Kasai

Hirokazu Tanaka

Motohiro Yamazaki

Naoki Yamashita

Hiromi Yamashita

Kazuhiko Nishiyama

Toshikazu Tanaka

Wataru Matsuo

Atsushi Fukumoto

Junji Shiokawa

Masahito Ito

Hiroyuki Noda

Eric S Nordman

Dai Yamamoto

Yoko Sato

Satoshi Takahashi

Yoshihiro Nagaoka

Naoshi Itabashi

Tatsuya Ide

Akihito Nishizawa

Toru Yokoyama

Shoei Teshima

Jun Abei

Akira Maekawa

Takanobu Haga

Miho Ozawa

Yukio Ono

Yoshiyuki Oya

Akira Doi

Hitoshi Miyata

Jin Matsumura

Takahiro Shinoda

Yuichiro Ota

Takamichi Muramatsu

Toshifumi Mitsuyama

Sonoko Migitaka

Yuusuke Kitoh

Shusuke Otsuki

Yoshihiko Kyo

Toshiyuki Sakurai

Hidenori Namba

Naoto Goto

Junji Ishizuka

Koichi Nakashita

An aluminum alloy heat exchanger includes a core material formed of an aluminum alloy comprising Mn of 0.60 to 2.00 mass % and Cu of 1.00 mass % or less, with the balance being Al and inevitable impurities, and a sacrificial anode material formed of an aluminum alloy comprising Zn of 2.50 to 10.00 mass %, with the balance being Al and inevitable impurities. Pitting potential of a sacrificial anode material surface of a tube of the aluminum alloy heat exchanger in a 5% NaCl solution is −800 (mV vs Ag/AgCl) or less, and pitting potential of an aluminum fin of the aluminum alloy heat exchanger in a 5% NaCl solution is less than the pitting potential of the sacrificial anode material surface of the tube of the aluminum alloy heat exchanger in a 5% NaCl solution.

Aluminum alloy heat exchanger

An image capturing mechanism includes: an optical measurement unit for optically observing a sample; a temperature conditioning unit for heating or cooling the sample, the temperature conditioning unit being mounted on a table by means of a support member; and a moving mechanism for moving the table in order to photograph the sample. The temperature conditioning unit includes: a temperature conditioning part for heating or cooling the sample, abutted on one face of a Peltier device; a heat conducting member abutted on the other face of the Peltier device; and the support member for holding the temperature conditioning part and the heat conducting member and securing the temperature conditioning part and the heat conducting member on the table. At least the heat conducting member is connected to a cooling means, and the thermal conductivity of the support member is low relative to the thermal conductivity of the heat conducting member.

Imaging mechanism and sample analyzing apparatus provided with the same

An aluminum alloy includes: a core material made of an aluminum alloy including Si, Cu, and Mn, with the balance being Al and unavoidable impurities; a brazing material cladded onto one side surface of the core material, and made of an aluminum alloy including Si, with the balance being Al and unavoidable impurities; and a sacrificial anode material cladded onto the other side surface of the core material, and made of an aluminum alloy including Zn and Si, with the balance being Al and unavoidable impurities, wherein a total number density of single phase pure Si and a intermetallic compound existing in the sacrificial anode material and having a grain size of 0.1 &#x3bc;m or more and 1.0 &#x3bc;m or less is 1&#xd7;10/mmor more and 1&#xd7;10/mmor less.

Aluminum alloy brazing sheet and method for manufacturing the same

In order to reduce the cost of producing a spot array substrate and reduce the cost of nucleic acid polymer analysis, a spot array substrate is used which is produced by preparing a resin substratehaving a surface on which an uneven pattern is formed and a plurality of bead sitting positions set in a two-dimensional array within the uneven pattern, and loading surface-modified beads onto the bead sitting positions of the resin substrate.

Spot array substrate, method for producing same, and nucleic acid polymer analysis method and device

A three-layer clad material includes a core material, a cladding material, and a cladding material, the core material including an aluminum alloy that includes 0.5 to 1.8% of Mn, and either or both of more than 0.05% and less than 0.2% of Cu, and 0.05 to 0.30% of Ti, with the balance being Al and unavoidable impurities, the cladding materialincluding an aluminum alloy that includes 3 to 10% of Si, and 1 to 10% of Zn, with the balance being Al and unavoidable impurities, and the cladding materialincluding an aluminum alloy that includes 3 to 13% of Si, and 0.05% or less of Cu, with the balance being Al and unavoidable impurities, wherein the Si content X (%) in the cladding materialand the Si content Y (%) in the cladding materialsatisfy the value (Y&#x2212;X) is &#x2212;1.5 to 9%.

Aluminum alloy cladding material for heat exchanger

A multicolor fluorescence analysis device is provided. The device includes a first fiberoptic plate for guiding light including fluorescence emitted from a sample as a result of irradiation of excitation light and emitting the same from a first emission part. The device includes a second fiberoptic plate for receiving light emitted from the first emission part at a second incidence part, guiding the same, and emitting the same from a second emission part. The device includes a single multilayer dielectric interference film filter that is provided on an end surface of the second emission part, transmits at least a portion of the fluorescence, and transmits light of a plurality of transmission wavelength bands that do not include the excitation wavelength bands. The device includes a two-dimensional detection unit that is disposed so as to be adhered to the multilayer dielectric interference film filter.

Multicolor fluorescence analysis device

An aluminum alloy clad material includes a core material, one side being clad with cladding material, the other side being clad with cladding material, the core material including an aluminum alloy that includes 0.5 to 1.8% of Mn, and limited to 0.05% or less of Cu, with the balance being Al and unavoidable impurities, the cladding materialincluding an aluminum alloy that includes 3 to 10% of Si, and 1 to 10% of Zn, with the balance being Al and unavoidable impurities, and the cladding materialincluding an aluminum alloy that includes 3 to 13% of Si, and limited to 0.05% or less of Cu, with the balance being Al and unavoidable impurities, wherein the Si content X (%) in the cladding materialand the Si content Y (%) in the cladding materialsatisfy the value (Y&#x2212;X) is &#x2212;1.5 to 9%.

The substratefor use in the analysis of a nucleic acid according to the present invention has multiple analysis areaswhich are partitioned on a substrate, and enables the measurement of the analysis areaswhile interchanging the analysis areasin turn, said substratebeing characterized in that each of the analysis areasconsists of an adsorption partonto which a DNA fragment or a carrier having the DNA fragment carried thereon can be adsorbed and a non-adsorption partwhich is a part outside of the adsorption part, and the non-adsorption parthas, formed on at least a part thereof, a marker partthat has a specified shape and helps to identify the positions of the analysis areas

Nucleic acid analysis device

A multicolor fluorescence analysis deviceis for detecting fluorescence emitted, as a result of excitation light irradiation, from a plurality of types of fluorophores included in a sample s, and is provided with an irradiation optical unitfor irradiating light emitted from a light sourceonto a sample s as excitation light, a fluorescence condensation unithaving a fluorescence filterthat transmits light emitted from the sample s and transmits light of transmission wavelength bands different from the excitation wavelength bands, and a two-dimensional detectorthat has a plurality of types of transmission filtersfor transmitting prescribed wavelengths of light and detects the intensity of the light of the prescribed wavelength for each transmission filter, and the light emitted from at least two fluorophores from among the plurality of types of fluorophores is detected simultaneously and the fluorophore types are identified accordingly.

By slowing down the passing velocity of a DNA molecule in a nanopore, the accuracy of the reading of a nucleotide sequence of DNA is improved. A small temperature difference is introduced between a DNA molecule having an asymmetric and periodic structure and a nanopore membrane that carries the DNA molecule, whereby the DNA molecule that passes through a nanopore can move in one direction and the passing velocity of the DNA molecule in the nanopore can be controlled and reduced. In this manner, the accuracy of the analysis of a nucleotide sequence can be improved. Furthermore, it becomes possible to dissociate double-stranded DNA into single-stranded DNA molecules by the action of temperature and subject the single-stranded DNA molecules to a measurement selectively. Furthermore, it also becomes possible to select the polarity of a DNA molecule and subject the DNA molecule to a measurement.

Analysis device

Provided is a flow cell for nucleic acid analysis used for a sequence reaction with photocleavable nucleotides where an efficiency of the photocleaving reaction can be enhanced and noise upon florescence detection can be mitigated, thereby improving the accuracy of sequencing, shortening a runtime, and extending a read length. The flow cell for nucleic acid analysis includes a first substrateprovided with an optical filterreflecting first light for changing a chemical structure of a substance in a flow passage, a hollow sheethaving a hollow portion for forming the flow passage, and a second substratetransmitting the first light, in which the first substrate, the hollow sheet, and the second substrate are attached to each other.

Flow cell for nucleic acid analysis and nucleic acid analyzer

A nucleic acid analysis device which can determine a DNA sequence has a flowcell in which two or more DNA fragment clusters of two or more DNA fragments having identical nucleotide sequences are immobilized. At least a part of the flowcell is made of a transparent material. An irradiation unit irradiates a part in which the DNA fragment clusters are immobilized. The device has a lens for collecting fluorescence, and a light-detection element. A solution containing only dATP having a fluorescently modified phosphate terminal among four bases, a solution containing only dCTP having a fluorescently modified phosphate terminal among the four bases, a solution containing only dGTP having a fluorescently modified phosphate terminal among the four bases, a solution containing only dTTP having a fluorescently modified phosphate terminal among the four bases, and a buffer solution are sent sequentially to where the DNA fragment clusters are immobilized.

The invention provides a capillary electrophoresis apparatus which can improve the operability and measuring speed. According to the invention, a sensor for identifying the type of sample containers is fixed at the position away from a capillary anode electrode. The sensor is made to be closer to the sample containers by moving a moving stage so that the sample containers disposed on the moving stage can be identified by the sensor. A fixing apparatus for fixing at least a pair of sample containers is provided on the moving stage.

Capillary electrophoresis apparatus

Capillary array for DNA sequencer

There is provided a capillary electrophoresis apparatus wherein coupling efficiency of exciting irradiation light to a capillary array does not decline even if any one capillary array of two capillary arrays is removed. Light emission generated by capillaries of each capillary array of 2(n is a positive integer) capillary arrays radiating exciting light from one side is detected by one optical detection system.

Growing community of inventors

Hitachinaka, Japan

Tomohiro Shoji