Megakaryon Corporation

Kyoto University

Satake Chemical Equipment Mfg. Ltd.

Tomohiro Shigemori

Haruki Okamoto

Koji Eto

Sou Nakamura

Yukitaka Ito

Yoshikazu Kato

Hiroshi Endo

Takeaki Dohda

Chisato Tokikura

The present invention provides a method for producing platelets, including the step of culturing megakaryocyte cells in a culture solution in a culture vessel, wherein in the culturing step, the culture solution is stirred by a stirring blade moving reciprocally.

Method for producing platelets using reciprocating stirring device

The present invention provides a method for producing platelets that can improve at least one of the ability of megakaryocyte to produce platelets and the bioactivity of platelets produced even in high-density culture, for example. The method for producing platelets of the present invention includes a platelet producing step of producing platelets from megakaryocytes, wherein the platelet producing step is performed in the presence of at least one of glycine and cysteine.

Method for producing platelets, method for producing platelet product, and method for producing blood product

The present invention provides a highly functional platelet production promoting agent which comprises one or a plurality of aryl hydrocarbon receptor (AhR) antagonists and one or a plurality of Rho-associated coiled-coil forming kinase (ROCK) inhibitors.

Method for producing highly functional platelets

The present invention provides a method for producing platelets, and the method comprises a step of culturing megakaryocytes in a culture solution in a culture vessel, wherein the culture solution is stirred with a stirrer in the culture step.

Method for manufacturing platelets by rotary stirring culture method

Growing community of inventors

Kyoto, Japan

Tomohiro Shigemori