Hokkaido University

Mochida Pharmaceutical Co., Ltd.

Tomohiro Onodera

Norimasa Iwasaki

Hitoshi Mizuno

Tomokazu Takai

Toshiya Endo

Koji Iwasaki

Akira Takahashi

Masahiko Katayama

Eiji Kondo

Wooyoung Kim

Yasuyuki Kawaguchi

Shinichi Sakaue

Kuniyoshi Masuda

Realized is reliable fixation of a material in a fluid state containing a monovalent metal salt of alginic acid when the material is applied to a subject. A combination of compositions comprising a first material composition containing a monovalent metal salt of alginic acid and a second material composition containing a cross-linking agent having an action of cross-linking the monovalent metal salt of alginic acid, wherein the combination is to be used in such a way as to apply the first material composition to a subject in a fluid state and contact the second material composition with the first material composition applied to the subject to gel at least a part of the first material composition, wherein the first material composition further contains a coloring component so that a formation state of a gel coat on a surface of the first material composition applied to the subject can be evaluated.

Combination and method for treating subject using alginate

A retractor is provided that can form a joint cavity internal space for a field of view for an endoscope and practice of a treatment in a state where a wound area is spread. A retractor includes first arm portionsandand a second arm portionpositioned between the first arm portionsand. The first arm portionsandinclude first claw portionsandto be hung on a wound area entrance edge. The second arm portionincludes a second claw portionto be hung on the wound area entrance edge. When the first arm portionsandand the second arm portionare in a closed state, the first claw portionsandand the second claw portionoverlap with each other.

Retractor

The present invention has an objective of providing a novel composition for treating a fibrocartilaginous tissue injury. The present invention provides a composition for treating a fibrocartilaginous tissue injury, which is to be applied to an injured fibrocartilaginous tissue part of a target and which comprises a monovalent metal salt of alginic acid, more preferably a low endotoxin monovalent metal salt of alginic acid.

Composition for treating fibrocartilage tissue damage

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Hokkaido, Japan

Tomohiro Onodera