Teikoku Seiyaku Co., Ltd.

Drossapharm Ag

Tomohiro Ishima

Hideo Kaneda

Masahiro Yamaji

Mamoru Naruse

Kazuo Kanai

Takashi Sekine

Shinichi Ota

Tomonari Yoshimura

Hiroyuki Yamasaki

Since treatment effects of conventional external preparations were not satisfactory, it is aimed to provide a novel external preparation that is excellent in drug permeability to nail, capable of fully exhibiting effects of an antifungal drug, and effective for treatments of diseases such as nail mycosis and nail candidiasis, particularly, treatments for nail tinea. The external preparation of this invention is a pharmaceutical composition for nail characterized by containing an antifungal drug, alkylpyrrolidone or a derivative thereof, and a crosslinking hydrogel.

Pharmaceutical composition for application to nail

The present invention provides to patches having excellent skin-permeability and therapeutic effect by the drug with lower irritation. In an external patch in which an adhesive layer containing an adhesive base and a drug are laminated with a backing, the external patch wherein the adhesive base contains 5-50% by weight of synthetic rubber polymer, 10-60% by weight of adhesive resin and 25-60% by weight of liquid paraffin, and the drug is etofenamate. According to the present invention, there is obtainable the patches having excellent skin-permeability and therapeutic effect by the drug with lower irritation.

External patches containing etofenamate

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Higashikagawa, Japan

Tomohiro Ishima