Pola Chemical Industries, Inc.

Tomoaki Yahiro

Takayuki Namiki

Naoki Hiyama

Masayuki Yuasa

Yukio Kawazu

Masashi Tamai

Satoshi Ichinomiya

Takako Takakuwa

Mayumi Sugio

Kenichi Kishii

Mariko Harada

Norio Funayama

Kyoko Taneda

The invention relates to a therapeutic and preventive medicament for respiratory diseases, comprising, as an active ingredient, a compound represented by the general formula (1):

Pyrrolo&lsqb;3,2-e&rsqb;pyrazolo&lsqb;1,5-a&rsqb;pyrimidine remedies/preventives for respiratory diseases

The invention relates to compounds represented by the following general formula (1): ##STR1## wherein R.sup.1 represents an alkyl group, R.sup.2 represents an amino group, alkyl group or the like, and R.sup.3 represents a nitro group, amino group, heterocyclic group, alkylsulfonylamino group or the like, or salts thereof, medicines comprising such a compound, a preparation process of the compounds, and intermediates useful for preparation thereof. The compounds (1) are useful for the prevention and treatment of a respiratory disease.

Pyrrolopyrazolopyrimidine compound and medicine comprising the same as

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Yokohama, Japan

Tomoaki Yahiro