Vicore Pharma Ab

Astrazeneca Ab

Tomas Fex

Bengt Ohlsson

Anders Rudolf Hallberg

Daniel Tor Pettersen

Mats Larhed

Leifeng Cheng

Jonas Boström

Johan Raud

Nadia Nasser Petersen

Michael Karle

Peter Schell

There is provided pharmaceutical compounds of formula I, wherein R, R, R, R, R, R, Y, Y, Y, X and Z have meanings given in the description, which compounds are useful in the treatment of autoimmune and/or fibrotic diseases, including interstitial lung diseases, such as idiopathic pulmonary fibrosis and sarcoidosis.

Selective angiotensin II compounds

There is provided herein a compound of formula I, wherein R, R, RY, Y, Y, Y, R, Rand Rare as defined herein, which compounds are useful in the treatment of autoimmune and/or fibrotic diseases, including interstitial lung diseases, such as idiopathic pulmonary fibrosis and sarcoidosis.

Compounds

or a pharmaceutically suitable salt thereof, wherein,

Isoxazol-3(2H)-one analogs as therapeutic agents

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Mölndal, Sweden

Tomas Fex