General Electric Company

Tomas Eriksson

Jonas Norling

Martin Pärnaste

Johan Larsson

Oskar Svedberg

Bert Holmgren

Peter Askebro

Vasile Bogdan Neculaes

Yong Liang

George Theodore Dalakos

Martin Orbe

Magnus Bondeson

Per Dahlberg

Simon Kinloch

Magnus Wallen

Janas Norling

Jonas Ove Norling

System includes a particle accelerator configured to direct a particle beam of charged particles along a designated path. The system also includes an extraction device positioned downstream from the particle accelerator. The extraction device includes a stripper foil and a foil holder that holds the stripper foil. The foil holder is configured to position the stripper foil across the designated path of the particle beam such that the particle beam is incident thereon. The stripper foil is configured to remove electrons from the charged particles, wherein the stripper foil includes a backing layer and a conductive layer stacked with respect to one another. The backing layer includes synthetic diamond.

Electron stripper foils and particle accelerators having the same

Target assembly includes a target body having a production chamber and a beam passage. The target body includes first and second grid sections that are disposed in the beam passage. Each of the first and second grid sections has front and back sides. The back side of the first grid section and the front side of the second grid section abut each other with an interface therebetween. The back side of the second grid section faces the production chamber. The target assembly also includes a foil positioned between the first and second grid sections. Each of the first and second grid sections has interior walls that define grid channels through the first and second grid sections. The particle beam is configured to pass through the grid channels toward the production chamber. The interior walls of the first and second grid sections engage opposite sides of the foil.

Target assembly and isotope production system having a grid section

Target assembly for an isotope production system. The target assembly includes a target body having a production chamber and a beam cavity that is adjacent to the production chamber. The production chamber is configured to hold a target material. The beam cavity opens to an exterior of the target body and is configured to receive a particle beam that is incident on the production chamber. The target assembly also includes a target sheet positioned to separate the beam cavity and the production chamber. The target sheet has a side that is exposed to the production chamber such that the target sheet is in contact with the target material during isotope production. The target sheet includes graphene.

Isotope production system having a target assembly with a graphene target sheet

Target assembly for an isotope production system. The target assembly includes a target body having a production chamber and a beam cavity that is adjacent to the production chamber. The production chamber is configured to hold a target liquid. The beam cavity opens to an exterior of the target body and is configured to receive a particle beam that is incident on the production chamber. The target assembly also includes a vibrating device that is secured to the target body. The vibrating device is configured to cause vibrations that are experienced within the production chamber.

Target assembly and isotope production system having a vibrating device

Production assembly for an isotope production system. The production assembly includes a mounting platform including a receiving stage that faces an exterior of the mounting platform. The mounting platform includes a beam passage that opens to the receiving stage and a stage port that is positioned along the receiving stage. A particle beam is configured to project through the beam passage and through the receiving stage during operation of the isotope production system. The stage port is configured to provide or receive a fluid through the receiving stage during operation of the isotope production system. The production assembly also includes a target assembly having a production chamber configured to hold a target material for isotope production. The target assembly includes a mating side that is configured to removably engage the receiving stage during a mounting operation.

Production assemblies and removable target assemblies for isotope production

A standalone radiopharmaceutical preparation hotcell for preparing a radiopharmaceutical includes a housing and a plurality of compartments defined within the housing. The plurality of compartments including at least a pharmaceutical synthesizing and dispensing compartment and a different second compartment, the synthesizing and dispensing compartment being maintained at a first pressure and the second compartment being maintained at a different second pressure using a compartment pressurization system.

Systems, methods and apparatus for manufacturing radioisotopes

A particle accelerator including an electrical field system and a magnetic field system that are configured to direct a particle beam of charged particles along a designated path within an acceleration chamber. The particle accelerator also includes a foil holder having a beam window and a positioning slot that at least partially surrounds the beam window. The positioning slot is dimensioned to hold an extraction foil such that the extraction foil extends across the beam window and into the path of the charged particles. The positioning slot is defined by interior reference surfaces that face the extraction foil and retain the extraction foil within the positioning slot. The reference surfaces permit the extraction foil to move relative to the reference surfaces when the particle beam is incident on the extraction foil.

Extraction system and particle accelerator having a foil holder

A self-shielding target for isotope production systems is provided. The target includes a body configured to encase a target material and having a passageway for a charged particle beam, and a component within the body, wherein the charged particle beam induces radioactivity in the component. Additionally, at least one portion of the body is formed from a material having a density value greater than a density value of aluminum to shield the component.

Self-shielding target for isotope production systems

A target apparatus for a radioisotope production system. The target apparatus includes a production chamber that is configured to contain a starting liquid. The production chamber is configured to receive a particle beam that is incident upon the starting liquid thereby generating radioisotopes and transforming a portion of the starting liquid into vapor. The target apparatus also includes a condensing chamber and a fluid channel that fluidly couples the production and condensing chambers and is configured to allow the vapor to flow from the production chamber to the condensing chamber. The condensing chamber is configured to transform the vapor into a condensed liquid.

Target apparatus and isotope production systems and methods using the same

Isotope production system including a particle accelerator configured to produce a particle beam. The isotope production system also includes a target apparatus having a window configured to receive a particle beam and also separate production and condensing chambers. The production chamber is configured to contain a starting liquid and located so that the particle beam is incident upon the starting liquid thereby generating radioisotopes and transforming a portion of the starting liquid into vapor. The target apparatus also includes a fluid channel that extends between and fluidly couples the production and condensing chambers. The fluid channel is configured to allow the vapor to flow from the production chamber into the condensing chamber. The condensing chamber is configured to transform the vapor in the condensing chamber into a condensed liquid.

Particle accelerators having extraction foils

A particle accelerator including an electrical field system and a magnetic field system that are configured to direct charged particles along a desired path within an acceleration chamber. The particle accelerator also includes a mechanical device that is located within the acceleration chamber. The mechanical device is configured to be selectively moved to different positions within the acceleration chamber. The particle accelerator also includes an electromechanical (EM) motor having a connector component and piezoelectric elements that are operatively coupled to the connector component. The connector component is operatively attached to the mechanical device. The EM motor drives the connector component when the piezoelectric elements are activated thereby moving the mechanical device.

Particle accelerators having electromechanical motors and methods of operating and manufacturing the same

A cyclotron that includes a magnet yoke having a yoke body that surrounds an acceleration chamber. The cyclotron also includes a magnet assembly to produce magnetic fields to direct charged particles along a desired path. The magnet assembly is located in the acceleration chamber. The magnetic fields propagate through the acceleration chamber and within the magnet yoke, wherein a portion of the magnetic fields escapes outside of the magnet yoke as stray fields. The cyclotron also includes a vacuum pump that is coupled to the yoke body. The vacuum pump is configured to introduce a vacuum into the acceleration chamber. The magnet yoke is dimensioned such that the vacuum pump does not experience magnetic fields in excess of 75 Gauss.

Isotope production system and cyclotron

A cyclotron that includes a magnet assembly to produce a magnetic field to direct charged particles along a desired path. The cyclotron also includes a magnet yoke that has a yoke body that surrounds an acceleration chamber. The magnet assembly is located in the yoke body. The yoke body forms a pump acceptance (PA) cavity that is fluidicly coupled to the acceleration chamber. The cyclotron also includes a vacuum pump that is configured to introduce a vacuum into the acceleration chamber. The vacuum pump is positioned in the PA cavity.

Isotope production system and cyclotron having a magnet yoke with a pump acceptance cavity

A cyclotron that includes a magnet yoke that has a yoke body that surrounds an acceleration chamber and a magnet assembly. The magnet assembly is configured to produce magnetic fields to direct charged particles along a desired path. The magnet assembly is located in the acceleration chamber. The magnetic fields propagate through the acceleration chamber and within the magnet yoke. A portion of the magnetic fields escape outside of the magnet yoke as stray fields. The magnet yoke is dimensioned such that the stray fields do not exceed 5 Gauss at a distance of 1 meter from an exterior boundary.

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Uppsala, Sweden

Tomas Eriksson