Basf Plant Science Gmbh

Basf Se Corporation

Tom Wetjen

Jörg Bauer

Xiao Qiu

Petra Cirpus

Guohai Wu

Martin Truksa

Bifang Cheng

Egon Haden

Alexander Wissemeier

Thorsten Jabs

Paul Cavell

Sarah Dunker

Joerg Bauer

Jorg Bauer

The present invention relates to polynucleotides fromwhich code for desaturases and elongases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides, and to the polypeptides encoded by the polynucleotides. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions.

Processes for producing polyunsaturated fatty acids in transgenic organisms

The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a &#x394;6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a &#x394;6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a &#x394;5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a &#x394;5 elongase activity, the nucleic acid sequence coding for a polypeptide with a &#x394;5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a &#x394;4 desaturase activity is also introduced into the plant.

Oils, lipids and fatty acids produced in transgenicplant

The invention relates to a method for producing eicosapentaenoic acid, docosapentaenoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a &#x394;6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a &#x394;6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a &#x394;5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a &#x394;5 elongase activity, the nucleic acid sequence coding for a polypeptide with a &#x394;5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a &#x394;4 desaturase activity is also introduced into the plant.

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Method for producing polyunsaturated fatty acids

The present invention relates to a composition, comprising a microorganism of speciesand at least one compound (II) in a synergistically effective amount.

Fungicidal compositions comprising a phosphate solubilizing microorganism and a fungicidally active compound

Growing community of inventors

Mannheim, Germany

Tom Wetjen