Shifamed Holdings, LLC

Boston Scientific Scimed, Inc.

Sadra Medical, Inc.

Biocircuits Corporation

Eunoe, Inc.

Covidien LP

Integra Lifesciences Corporation

Apama Medical, Inc.

Kalila Medical, Inc.

Csf Refresh, Inc.

Other

Nuvera Medical, Inc.

Mtex Cardio Ag

Chine, LLC

Sadra Medicl, Inc.

Tom Saul

Amr Salahieh

Claudio Argento

Dwight P Morejohn

Daniel K Hildebrand

Ulrich R Haug

Hans F Valencia

Brian D Brandt

Jean-Pierre Dueri

Robert Adam Geshlider

Jonah Lepak

Colin Mixter

John Patrick Claude

Bob Vaughan

Brady David Esch

Eric Willis

Emma Lepak

Daniel Varghai

Anna Kerlo

Hans Oliver Ribi

Robert T Chang

Richard S Lilly

Emma Leung

Katherine Sapozhnikov

Kenneth J Michlitsch

Ali Salahieh

Henry L Schwartz

Andrew Backus

Marvin L Sussman

Brice Arnault De La Menardiere

Clayton Baldwin

Cheryl A Cathey

Marc Bitoun

Andrea Johnson

Alan K Schaer

Michael J Drews

Joseph Creagan Trautman

Eric Schultz

Jaime Salvador Vargas

Adnan I Merchant

Richard Joseph Renati

Peter S Brown

Christopher T Cheng

Nicole Denise Bloom

Edward Rubenstein

David L Karshmer

Michael Calomeni

Elliott C Levinthal

Tom Witty

Shirley Johnson

Heidi Mathis

Jeffrey D Langford

Jeffrey B Langford

Kristof Hovaten

Suresh Subraya Pai

John C Spiridigliozzi

Jeff A Krolik

David J Paul

Arindam Datta

Syed Hasan Askari

Nicholas J Spinelli

John M MacMahon

Alice Yang

Todor Jeliaskov

Jasper Ellington Adamek-Bowers

Todd A Guion

Janine Robinson

Michael Conroy

Jury Schewel

Connor G Mulcahy

Karl-Heinz Kuck

Dawn McGuire

Juan Diego Perea

Paul Kenhey

Georges Der-Balain

Paul Kenney

Georges Der-Balian

Robert Edesess

John P Claude

Edward Brian MacMahon

Veronica Neiman

Robert A Gleshlider

Gerald Silverberg

Ryan William Boyd

Jacob Raquet

Jasper Ellington Adamek-bowers

Claudio R Argento

Dwight Morejohn

Robert Geshlider

Daniel Hildebrand

Cornelius Matthew Crowley

Cooper Burton

The present technology is directed to adjustable shunts for treating glaucoma. In particular, some embodiments provide shunts having a plurality of individually actuatable flow control elements that can control the flow of fluid through associated ports and/or flow lumens. For example, each individually actuatable flow control element can be actuated to block and/or unblock a corresponding port and/or flow lumen. Accordingly, the shunts described herein can be manipulated into a variety of configurations that provide different drainage rates based on whether the ports and/or flow lumens are blocked or unblocked, therefore providing a titratable glaucoma therapy for draining aqueous from the anterior chamber of the eye.

Adjustable flow glaucoma shunts and associated systems and methods

The present technology is directed to implantable medical devices for draining fluid from a first body region to a second body region. Some embodiments of the present technology provide adjustable devices that are selectively titratable to provide various levels of therapy. For example, the adjustable devices can have a drainage element with a lumen extending therethrough, a flow control element, and an actuation assembly. The actuation assembly can drive movement of the flow control element to change a dimension of and/or a flow resistance through the lumen, thereby increasing or decreasing the relative drainage rate of aqueous from an eye. In some embodiments, the actuation assembly and the flow control element together operate as a ratchet mechanism that can selectively move the flow control element between a plurality of positions and lock the device in a desired configuration until further actuation of the actuation assembly.

Adjustable glaucoma treatment devices and associated systems and methods

Catheter blood pump that include an expandable pump portion extending distally from an elongate shaft. The pump portions include an expandable impeller housing including an expandable blood conduit that defines a blood lumen between an inflow and an outflow. The pump portions include one or more expandable impellers disposed at least partially within the blood lumen.

Intravascular blood pumps and methods of manufacture and use

Methods and devices for supporting circulation. The methods may include positioning a blood pump in the arterial vasculature or the venous vasculature. The methods may include positioning a pump portion of the blood pump in a descending aorta, an inferior vena cava, a renal artery, and/or a renal vein. The methods include delivering a pump portion of a blood pump to a target location and rotating one or more impellers to move blood through the pump portion.

Descending aorta and vena cava blood pumps

An accommodating intraocular lens (AIOL) for implantation within a capsular bag of a patient's eye comprises first and second components coupled together to define an inner fluid chamber and an outer fluid reservoir. The inner region of the AIOL provides optical power with one or more of the shaped fluid within the inner fluid chamber or the shape of the first or second components. The fluid reservoir comprises a bellows region with fold(s) extending circumferentially around an optical axis of the eye. The bellows engages the lens capsule, and a compliant fold region between inner and outer bellows portions allows the profile of the AIOL to deflect when the eye accommodates for near vision. Fluid transfers between the inner fluid chamber and the outer fluid reservoir to provide optical power changes. A third lens component coupled to the first or second component provides additional optical power.

Multi-piece accommodating intraocular lens

Devices for moving blood within a patient, and methods of doing so. The devices can include a pump portion that includes an impeller and a housing around the impeller, as well as a fluid lumen. The impeller can be activated to cause rotation of the impeller and thereby move fluid within the fluid lumen.

Intravascular blood pumps and methods of use and manufacture

The present disclosure is directed to an expandable energy delivery assembly adapted to deliver electrical energy to tissue. The assembly includes an elongate device and an expandable portion. The expandable portion includes an inflatable element, a single helical electrode disposed on the inflatable element, and at least one irrigation aperture within the inflatable element. The inflatable element is secured to the elongate device and the single helical electrode makes between about 0.5 and about 1.5 revolutions around the inflatable element. The at least one irrigation aperture is adapted to allow fluid to flow from within the inflatable element to outside the inflatable element.

Energy delivery device and methods of use

An accommodating intraocular lens (AIOL) for implantation within a capsular bag of a patient's eye comprises first and second components coupled together to define an inner fluid chamber and an outer fluid reservoir. The inner region of the AIOL provides optical power with one or more of the shaped fluid within the inner fluid chamber or the shape of the first or second components. The fluid reservoir comprises a bellows region with one or more folds of the bellows extending circumferentially around an optical axis of the eye. The bellows engages the lens capsule, and a compliant fold region between the inner and outer bellows portions allows the profile of the AIOL to deflect when the eye accommodates for near vision. Fluid transfers between the inner fluid chamber and the outer fluid reservoir to provide optical power changes when the eye accommodates.

Accommodating intraocular lens

An energy delivery system for delivering electrical energy to tissue, includes an elongate catheter member defining a longitudinal axis and dimensioned for passage within a body vessel and an expandable treatment member mounted to the catheter member. The treatment member includes an inflatable element adapted to transition between an initial condition and an at least partially expanded condition upon introduction of an anesthetic solution within the inflatable element, an electrode for delivering electrical energy to at least the nerve tissue associated with the body vessel to cause at least partial denervation thereof and at least one aperture dimensioned to permit passage of the anesthetic solution from the inflatable element to contact the body vessel whereby the solution at least enters the body vessel to at least partially anesthetize the nerve tissue therewithin. The electrode may be mounted to at least the inflatable element of the treatment member and may be generally helical.

Intravascular blood pumps and methods of use

In particular, some embodiments provide shunts having a plurality of individually actuatable flow control elements that can control the flow of fluid through associated ports and/or flow lumens. For example, each individually actuatable flow control element can be actuated to modify a flow of a corresponding port and/or flow lumen. The individually actuatable flow control elements may be actuated along a given actuation axis. A flow control assembly may include a plurality of flow control elements arranged about a collection region. Accordingly, the shunts described herein can be manipulated into a variety of configurations that provide different drainage rates based on a degree to which the ports and/or flow lumens are blocked or unblocked, therefore providing a titratable glaucoma therapy for draining aqueous from the anterior chamber of the eye.

Adjustable flow glaucoma shunts having non-linearly arranged flow control elements, and associated systems and methods

An intravascular fluid movement device that includes an expandable member having a collapsed, delivery configuration and an expanded, deployed configuration, the expandable member having a proximal end and a distal end, a rotatable member disposed radially and axially within the expandable member, and a conduit coupled to the expandable member, the conduit at least partially defining a blood flow lumen between a distal end of the conduit and a proximal end of the conduit, the conduit disposed solely radially inside of the expandable member in a distal section of the expandable member.

Intravascular fluid movement devices, systems, and methods of use

An ablation catheter including an elongate shaft, an inflatable balloon positioned at a distal region of the elongate shaft, a first ablation electrode disposed outside of and carried by an outer surface of the inflatable balloon, a first ultrasound transducer disposed outside of the inflatable balloon, and a flexible circuit. The flexible circuit includes a first conductor and a second conductor and is disposed outside of and carried by the outer surface of the inflatable balloon. The first conductor is in electrical communication with the first ablation electrode, and the second conductor in electrical communication with the first ultrasound transducer.

Tissue ablation and monitoring thereof

Growing community of inventors

El Granada, CA, United States of America

Tom Saul