Kanebo, Limited

Ghen Corporation

Isamu Fujita

Toshio Horikoshi

Junichiro Hiraoka

Tohru Tokoro

Hideaki Yokoyama

Yoshikatsu Kodama

Cell-associated glucosyltransferase of S. mutans serotypes c, e or f producing dental caries was isolated and purified and its characteristics as an enzyme were revealed. Furthermore, an antibody against said enzyme was prepared from eggs of the hens immunized with said enzyme. Since this antibody effectively prevents adherence of the aforementioned S. mutans to tooth surfaces, it is useful as an effective component for a dental caries prophylactic composition.

Cell-associated glucosyltransferase, an antibody thereto, and a dental

Cell-associated glycosyltranferase of S. mutans serotypes c, e or f producing dental caries was isolated and purified and its characteristics as an enzyme were revealed. Furthermore, an antibody against the enzyme was prepared from eggs of the hens immunized with the enzyme. Since this antibody effectively prevents adherence of the aforementioned S. mutans to tooth surfaces, it is useful as an effective component for a dental caries prophylactic composition.

Cell-associated glucosyltransferase from Streptococcus mutans serotype,

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Gifu, Japan

Tohru Tokoro