Suntory Limited

Tohru Kodama

Mitsuru Maeda

Norihide Amano

Koichi Nakahara

Sumio Asami

Takaaki Kusumi

Naoki Higuchi

Masayuki Saitoh

Tomohiko Ogawa

Norio Iwasawa

Hidekazu Hosono

Yasuo Igarashi

Wataru Fujii

Katsuro Miyagawa

Hyaluronidase inhibitor containing GOD-type ellagitannin as an active ingredient, as well as pharmaceuticals and cosmetics containing the inhibitor. The activity of hyaluronidase which hydrolyses hyaluronic acid can be inhibited without causing any toxicity to human, notably in the absence of irritation or any other adverse effects on the skin.

Hyaluronidase inhibitor containing god-type ellagitannin as active

Disaccharide derivative

The nucleotide sequence of a DNA coding for highly thermophilic cytochrome C-552, a plasmid containing said sequence, a host cell transformed with said plasmid and a process for the production of C-552 comprising culturing said host.

Cytochrome C gene derived from hydrogen bacterium

Novel peptide analogues which exhibit inhibitory activity against aspartic proteinases, a novel species of actinomycetous microorganism which produces said novel peptide analogues, a process for producing said novel analogues by culturing said species and a pharmaceutical composition containing said analogues.

Enzyme inhibitor and method of producing the same

A 2-pyranone derivative represented by the formula (I): ##STR1## wherein R represents a hydrogen atom, or a linear, branched alkylcarbonyloxy, or cyclo-alkylcarbonyloxy group having 3 to 10 carbon atoms, and salts thereof; a process for the production of the above-mentioned 2-pyranone derivative (I), comprising the steps of culturing a microorganism belonging to the genus Streptomyces and capable of producing the derivative, to produce the derivative, and recovering the produced derivative from the cultured product; a biocidal composition comprising the above-mentioned 2-pyranone derivative (I); and a microorganism belonging to the genus Stretromyces and capable of producing the above-mentioned 2-pyranone derivatives.

2-pyranone derivative and process for production thereof

Growing community of inventors

Osaka, Japan

Tohru Kodama