Acist Medical Systems, Inc.

Todd Suchecki

Robert Foster Wilson

Paul Anthony Pilosi

Nathaniel R Hallee

Jonathan Barrett

Martin G Hieb

Alan Evans

Thomas M Snyder

Deborah Jean Brown

Jung Wook Suh

Jason Ness

William Harm

Bryan Brutlag

Andrew Youel

Edward Miller

Ryan Whitehouse

James Engel

Jung W Suh

Benjamin Priess

Todd Oliverius

Embodiments for assessing flow at an anatomical region of interest are disclosed. One embodiment uses pulsed contrast media injections at a known frequency along with corresponding image data to derive a measurement of blood flow velocity at the region of interest. Another embodiment uses incremental changes in known contrast media injection flow rates to match the blood flow rate relative to one of these known contrast media injection flow rates based on the presence of a particular indicia in image data. For example, this indicia can be the flow of contrast media out from a coronary artery back into the aorta or the onset of a steady state pixel density. A further embodiment uses contrast media injections that are synchronized with the cardiac cycle. For example, contrast media injections can be synchronized with the diastolic and/or systolic phases and used to measure blood flow accordingly.

Flow measurement using image data

One method for assessing a vessel can include obtaining a set of first location pressure measurements at a first location in the vessel over a first time period and a set of second location pressure measurements at a second location in the vessel over the first time period. This method can further include identifying a first leading characteristic associated with one or more pressure measurements in the set of first location pressure measurements, a second leading characteristic associated with one or more pressure measurements in the set of second location pressure measurements, a first trailing characteristic associated with one or more pressure measurements in the set of first location pressure measurements, and a second trailing characteristic associated with one or more pressure measurements in the set of second location pressure measurements. And, this method can include calculating a pressure ratio using pressure measurements between the identified characteristics.

Assessment of a vessel

Described herein are methods and systems for calculating a corrected Fractional Flow Reserve (FFR). An illustrative method includes delivering a first pressure sensing device including a pressure sensor to a location in a blood vessel having a stenosis, positioning the pressure sensor distal to the stenosis, measuring the distal pressure, measuring the proximal pressure, and calculating a corrected FFR using the measured proximal and distal pressures and applying a correction factor or correction equation. The corrected FFR may approximate a FFR that would have been obtained if the pressure measured downstream of the stenosis was measured using a second pressure sensing device having a second maximum cross-sectional area in a distal portion of the second pressure sensing device that is different from the first maximum cross-sectional area.

Intravascular sensing method and system

Methods and systems for calculating a corrected Fractional Flow Reserve. Methods include delivering a pressure sensing device including a pressure sensor to a location in an artery having a stenosis, positioning the pressure sensor distal to the stenosis, measuring the distal pressure, measuring the proximal pressure, and calculating a corrected Fractional Flow Reserve using the measured proximal and distal pressures and applying a correction factor or correction equation. The correction factor or correction equation corrects for changes in the measured distal pressure caused by a presence of the pressure sensing device. A data set of correction factors or correction equations may be stored in a memory component of the system. The corrected Fractional Flow reserve may approximate the Fractional Flow Reserve that would be obtained if a different sized device was used to measure the distal pressure, such as a pressure sensing guidewire having a 0.014 inch outer diameter.

One implementation provides a method to provide injection procedure information in an injection system. In this implementation, the method includes displaying a plurality of different injection procedure options in a user interface of said system, wherein said plurality of different injection procedure options including a cardiac procedure option and a non-cardiac procedure option. The method further includes receiving a user selection of an injection procedure from said displayed plurality of difference injection procedure options, processing a default set of injection parameters based upon said selected injection procedure, and displaying said default set of injection parameters within the user interface of the system prior to an injection.

Medical fluid injection system

Growing community of inventors

Robbinsdale, MN, United States of America

Todd Suchecki