Mcmaster University

Todd Hoare

Yingfu Li

Leyla Soleymani

Jonathan Dorogin

Maryam Badv

David Koff

Andrew Singh

Lukas Sadowski

Xudong Deng

Yang Lu

Haiming (Daniel) Luo

Dingran Chang

Nahieli Iyeida Preciado Rivera

Niels M B Smeets

Zhicheng Pan

Emilia Bakaic

Richa Pandey

The disclosure relates to an in situ-gelling hydrogel composition based on functionalized zwitterionic polymers. The resulting hydrogels exhibit highly anti-fouling, anti-adhesive, and lubricating properties to enable the fabrication of bulk hydrogels or hydrogel-based coatings of relevance to biomedical applications.

In situ gelling zwitterionic hydrogel compositions, and methods of use thereof

The present application relates to a vehicle whose shell material is modified with at least one additional secondary phase that acts as a cork. In the presence of an energy source (preferably ultrasound), the corks embedded in the shell are either removed from the shell to create permanent pores or perturbed within the shell to create transient pores that can control transport in or out of the vehicle.

Stimulus activated cork-shell capsules

The present application relates to brush amphiphilic block copolymers comprising at least one block which is hydrophilic and at least another block which is hydrophobic. The block copolymers can be used to prepare nanoparticles for biomedical applications including delivery of pharmaceuticals and other bioactive agents

Brush amphiphilic block copolymers, and self-assembled nanoparticles therefrom

The present application relates to hydrogel compositions comprising first and second precursor polymers, wherein the precursor polymers are modified poly(oligoethylene glycol methacrylate) copolymers that are crosslinked through electrophile-nucleophile reactions.

Poly(oligoethylene glycol methacrylate) hydrogel compositions, and methods of use thereof

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Ancaster, Canada

Todd Hoare