Sugen Incorporated

Other

Proquest LLC

Ligand Pharmaceuticals, Inc.

Pharmacia & Upjohn Company

Agouron Pharmaceuticals, Inc.

Webfeat, Inc.

Todd Anthony Miller

Peng Cho Tang

Li Hsiang Sun

Congxin Liang

Asaad S Nematalla

Xiaoyuan Li

Paul Duncan

Brian Schelp

Chung Chen Wei

Ngoc My Tran

Anh Thi Nguyen

Shahrzad Shirazian

Tomas Vojkovsky

Michael John Hawley

Lin Zhi

Dean Paul Phillips

Jyun-Hung Chen

Thomas Lau

E Adam Kallel

Jackline Eve Dalgard

Matthew McNeill

Daniel A Ruppar

Pen Cho Tang

Gerald McMahon

Bao Vinh Nguyen

Ping Huang

Connie Li Sun

G Davis Harris

Bao Ngoc Nguyen

Ruofei Zhang

Richard Julius Penuliar

Kenneth E Lipson

Richard J Penulian

Jinrong Cui

Chung Chun Wei

Bao N Nguyen

Adam E Kallel

Jackline E Dalgard

Richard J Penulair

An intraoral x-ray imaging sensor includes an electronic interface substrate which has a first surface and a second surface and is substantially rectangular with a mesial end and a distal end and a semiconductor imager which is mechanically and electrically coupled to the electronic interface substrate and which has a first surface and a second surface. The semiconductor imager consists of a silicon layer having an array of detector elements formed on its the first surface and is substantially rectangular with a mesial end and a distal end. The electronic interface substrate and the semiconductor imager have a first cut corner and a second cut corner at its the distal end. The second surface of the semiconductor imager is disposed adjacent and contiguous to the first surface of the electronic interface substrate. The intraoral x-ray imaging sensor also includes a plurality of first electrical pads, a plurality of second electrical pads and a plurality of bond wires. The first electrical pads are disposed on the first surface of the electronic interface substrate wherein some of the first electrical pads are disposed adjacent and contiguous to the first cut corner and the remainder of the first electrical pads are disposed adjacent and contiguous to the second cut corner. The second electrical pads are disposed on the first surface of the semiconductor imager wherein some of the of second electrical pads are disposed adjacent and contiguous to the first cut corner and the remainder of the second electrical pads are disposed adjacent and contiguous to the second cut corner. Each bond wire electrically couples one of the first electrical pads to one of the second electrical pads.

Intraoral dental radiological imaging sensor

The present invention generally relates to a method and system for retrieving search results. More particularly, the present invention relates to a method and system for retrieving search results concurrently from multiple disparate databases, whether such databases be available through the Web, or other proprietary internal networks. In an exemplary embodiment, the system includes a user interface, a control engine, and a number of translators which are used to communicate with a number of corresponding databases. During exemplary operation, a user uses the user interface to enter search term(s) and other pertinent information relating to his/her search and specify which ones of the databases are to be searched. The search term(s) and other pertinent information are then relayed to the control engine which, in turn, forwards them to the appropriate translators which correspond to the specified databases to be searched. These translators then concurrently formulate and issue their respective search requests to the corresponding databases. Concurrent searches are then carried out in the specified databases. Search results from each of the specified databases are then returned and consolidated for display by the user interface.

Method and system for retrieving search results from multiple disparate databases

Systems and methods enable remote (or 'off-campus') users complete authorized access to full-record content of 3rd-party databases subscribed to by the user's institution. More particularly, the present invention relates to a method and system that acts as a transparent conduit between the user and a remote database, managing relevant session/context information without the user's awareness and without the need for users to install plug-ins or configure browser proxies.

Systems and methods for managing database authentication and sessions

Disclosed herein are compounds of Formula (I), (II), and (III) pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.

Thrombopoietin activity modulating compounds and methods

The present invention relates to pyrrole substituted-2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Pyrrole substituted 2-indolinone protein kinase inhibitors

The present invention relates to 5-sulfonamido substituted indolinones that modulate the activity of protein kinases ('PKs'). The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.

5-sulfonamido-substituted indolinone compounds as protein kinase inhibitors

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

The present invention relates to novel 3-methylidenyl-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

3-methylidenyl-2-indolinone modulators of protein kinase

The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.

Indolinone compounds as kinase inhibitors

The present invention relates to novel geometrically restricted 2-indolinones and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Geometrically restricted 2-indolinone derivatives as modulators of protein kinase activity

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Bend, OR, United States of America

Todd Anthony Miller