Boston Scientific Scimed, Inc.

Arsenal Medical, Inc.

Scimed Life Systems, Inc.

Arsenal Medial, Inc.

Aresenal Aaa, Llc.

Boston Scientific Corporation

Zugates, Gregory T.

Freyman, Toby

Sharma, Upma

Busold, Rany

Miller, Lisette, Manrique

Rago, Adam

Toby Freyman

Upma Sharma

Wendy Naimark

Maria Palasis

Rany Busold

Gregory T Zugates

Adam Rago

Quynh P Pham

Parisa Zamiri

Irina Gitlin

Timothy J Mickley

Jeffrey D Carbeck

Robert J Caulkins

Changcheng You

Samuel J Epstein

Jennifer Mortensen

John Marini

Tim J Mickley

William Joseph Shaw

Dennis R Boulais

Marlene C Schwarz

Joseph A Levendusky

Chad G Harris

Mark T Ungs

Michael Stephen Austin

Joseph Lomakin

Ruth Cheng

Praveen Kulkarni

Xuri Yan

Lisette Manrique Miller

Robert F Mulligan

Don Robinson

Meghan McGill

Dorin Panescu

Daniel James Horn

Lee A Core

Jeffrey Groom, Ii

Peter J Shank

Gordon Kocur

Kalpana Kamath

Matthew L Hawk

Jacob Rooney

Greg Zugates

Alexandra Rousseau

Shubhang Mishra

Inas Khayal

Janet Komatsu

Changchen You

Abby N Picard

John Caulkins

Daniel K Bonner

Anastasia Panos

Samuel Epstein

Tim Mickley

Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

In situ forming hemostatic foam implants

In situ forming hemostatic form implants

Delivery catheters for in situ forming foams are provided. The catheters include, in various embodiments, coatings, valves, mixing structures, exit ports and combinations of the same.

Delivery catheters for in situ forming foams

Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.

Delivery system for in situ forming foams and methods of using the same

Systems and methods related to polymer foams for the treatment of blood vessel dissections are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to or within a dissection caused by an intimal tear in a blood vessel, sealing the dissection and preventing further perfusion thereof. In some embodiments, the polymer foam can be formed within a body cavity (i.e., in-situ foam formation). The foam may be used to fill the dissection as a thrombosing agent. In addition, the foam may be used in conjunction with medical devices such as stents, stent-grafts, balloons, and catheters.

In-Situ forming foam for the treatment of vascular dissections

Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms are disclosed. The systems include an insertable medical device and an in-situ forming foam that is formed from a polymer that reacts in an aqueous environment. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.

In-situ forming foams for treatment of aneurysms

Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.

In-situ forming foams with outer layer

The present invention relates generally to the field of electrospun fibers. In particular, the present invention relates to core-sheath fibers and related electrospinning methods. The fibers of the invention comprise poorly water soluble drugs and/or proteins.

Fibers comprising poorly soluble drugs and/or proteins

The present invention relates generally to systems and methods and systems for generating polymer foams within body cavities to locate and/or control bleeding. The present invention further relates to methods and systems for generating polymer foams within non-compressible wounds to control or stop bleeding. The present invention further relates to the use of foams and gels for medical and cosmetic purposes.

Foam-based medical treatments

Growing community of inventors

Waltham, MA, United States of America

Toby Freyman