Boehringer Ingelheim Microparts Gmbh

Boehringer Ingelheim International Gmbh

Tobias Rodenfels

Gert Blankenstein

Dirk Kurowski

Mario Hempel

Berthold Lange

Wolfgang Stoeters

Markus Voigt

Dirk Osterloh

Sample liquid is collected in a chamber downstream of a separating device. Adjoining the chamber are a plurality of channels which guide the sample liquid to one or more investigating regions.

Apparatus and method for separating components of a sample liquid

The invention relates to a device and method for manipulating a liquid in a channel, wherein a body, which forms a capillary intermediate space with respect to the channel wall, is moved in the channel and the channel is filled with liquid only up to the body. Preferably, the body can also bridge an area of the channel that cannot be wetted for the liquid.

Device and method for manipulating a liquid

A device and a process are proposed for separating constituents of a sample fluid, wherein the sample fluid is supplied by capillary force to a receiving region () for metering, stopping or delaying the sample fluid and the sample fluid is pre-treated with a soluble chemical () in the receiving region () before the sample fluid is supplied to a separating device () for separating off constituents of the sample fluid.

Apparatus and method for separating constituent parts of a sample liquid

A device, particularly a microfluidic system, is proposed, in which two cavities are arranged spatially close to one another and are sealed off from one another by a common cover. A fluidic connection can be produced between the cavities by movement of a pin-shaped body towards the cover. In this way it is possible to release a reagent in controlled manner without having to put it under pressure.

Device and method for producing a fluidic connection between cavities

A microfluidic device meters liquids into a network of channels or chambers partly formed by a film partly attached to and above a substrate, the network permitting flow of fluid above the substrate. To form a channel or chamber, the edge zone between unattached and attached portions of the film forms a wedge of material by viscous flow of film material as the film is laminated to the substrate, this wedge forming a transition between the chamber wall and the substrate, raising the wall above the plane of the substrate. Film is laminated with a mask having an opening, the mask pressed onto the film under pressure and/or with heat. The film is brought to a temperature to produce a viscous flow of film and/or substrate medium into the region of the opening, forming a wedge of material as the film bulges up at the opening to form a chamber.

Microfluidic foil structure for metering of fluids

A device for the intake or manipulation of a fluid, in particular, a liquid, and a method for the production of a device of this type in which a flat, non-preformed covering film is laminated onto a carrier, a three-dimensionally shaped or convex chamber wall being formed solely by means of the laminating process. The chamber wall which forms a boundary of a chamber for the fluid is partially deformable. The device is simple to produce and can be used universally.

Growing community of inventors

Dortmund, Germany

Tobias Rodenfels