Hoechst Aktiengesellschaft

Aventis Pharma Deutschland, Gmbh

Solvay

Tobias Metzenthin

Gunter Siegemund

Frank Ebmeyer

Heinrich Christian Englert

Uwe Gerlach

Wolfgang Appel

Harald Schneider

The present invention relates to crystalline forms of the sodium salt of 5-chloro-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonylphenyl)ethyl)benzamide, processes for their preparation, their use, and pharmaceutical preparations comprising them.

Crystalline forms of the sodium salt of 5-chloro-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonylpenyl)ethyl)benzamide

The invention relates to the preparation of trifluoroacetyl fluoride by reacting trichloroacetyl chloride with anhydrous hydrogen fluoride in the gaseous phase on a catalyst which is obtainable by reacting a water-soluble chromium (III) salt with magnesium hydroxide or magnesium oxide in the presence of water, converting the reaction mixture into a paste, drying the paste and treating it with hydrogen fluoride.

Process for preparing trifluoroacetyl fluoride

The invention relates to a process for the preparation of trichloroacetyl chloride by reaction of acetyl chloride or acetaldehyde or chlorinated derivatives thereof with chlorine in the presence of active charcoal as the catalyst.

Process for the preparation of trichloroacetyl chloride

Process for preparing trifluoroethyl sulfur compounds from thiolates and 1-chloro-2,2,2-trifluoroethane. The invention relates to the preparation of trifluoroethyl sulfur compounds of the formula RSCH.sub.2 CF.sub.3 by reacting 1-chloro-2,2,2-trifluoroethane CH.sub.2 Cl--CF.sub.3 in a polar aprotic solvent with salts of thiols of the formula RSH, where R can be an alkyl or aryl radical or a heterocyclic radical.

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Frankfurt-am-Main, Germany

Tobias Metzenthin