Council of Scientific and Industrial Research

Tiruppadiripuliyur Ranganathan Santha Kumar

Suman Preet Singh Khanuja

Sushil Kumar

Mahendra Pandurang Darokar

Ajit Kumar Shasany

Dharmendra Saikia

Sunita Dhawan

Suchi Srivastava

Nirmal Kumar Patra

Krishna Kumar Agarwal

Janak Raj Bahl

Arun Kumar Tripathy

Sarita Satapathy

Madan Mohan Gupta

Jai Shankar Arya

Ajit Kumar Shasney

Prachi Sinha

Ateeque Ahmed

Atique Ahmad

Dharam Chand Jain

Raj Kishori Lal

Vivek Kumar Gupta

Ram Kishor Verma

Monika Singh

Santosh Kumar Srivastava

Yogendra Nath Shukla

Merajuddin Khan

Anil Srivastava

Subhash Chandra Singh

Digvijay Singh

Anita Gangwar

Subash Chandra Verma

Shalini Mathur

Srilekha Mishra

Subash Chandra Singh

Raghavendra Kumar Mishra

Ankur Grag

Arvind Kumar Tripathy

Puspalata Chatruvedi

Preeti Chand

Arif Ali Naqui

The present invention relates to an alpha-arteether resistance domain (ADR) of Sequence ID No.1 and a method of identifying ADR in alpha-arteether resistant pathogens and lastly, it relates to set three pairs of primers of sequence ID Nos. 3 to 8.

Alpha arteether resistance domain

The present invention provides an improved process for the isolation of oleane compounds from the bark of(Roxb.). More particularly, the present invention relates to an improved process for the isolation of arjunic acid and its derivates from the bark of(Roxb.). The present invention further provides the identification of arjunic acid [1] and its derivatives as anticancer agent useful in the treatment of various types of cancer in humans.

Process for the isolation of oleane compounds isolated from the bark of arjun tree terminalia arjuna (Roxb.)

The present invention relates to a method of testingresponse to abiotic stress factors and for testing bioactivity of natural, synthetic and semisynthetic compounds usingplant, which comprises growing the said plant and plant parts aseptically in MS 0 basal medium with agar in microcentrifuge tubes by adding the compounds to be tested either to the culture media or by spraying the said compounds on the plant or plant parts or on the said medium to detect the distinct morphological and cytological responses.

Plant test procedure to detect natural, semi-synthetic, synthetic compounds and physical stress factors through expression of distinct responses

An in vitro screening method for identifying insect tolerant genotypes or clones is described. The method comprises growing plantlets in an in vitro system, screening the plantlets for molecular variation of somaclones using RAPD analysis in vitro, selecting the somaclones having molecular variation, exposing the somaclones to insect larvae or nymphs and identifying the surviving somaclones.

Screening method for selection of insect tolerant plants

The present invention relates to a rapid, sensitive, simple, and cost-effective spectrophotometric method of detecting and quantifying mycolic acid in a mycolic acid-fuschin dye complex with absorbance maxima ranging between 490-500 nm in the presence of various test compounds, for screening mycolic acid biosynthesis inhibitors useful as anti-microbial agents and a diagnostic kit thereof comprising basic fuschin dye in the concentration ranging between 0.1-1.0 gm/100 ml, phenol and 95% ethanol in the ratio ranging between 1:4 to 2:1 (v/v), and phenol and distilled water in the ratio ranging between 1:14 to 1:25.

Quick and sensitive method of quantifying mycolic acid to develop anti-microbial agents and a diagnostic kit thereof

The present invention describes a novel and very quick bacterial system based screening protocol to detect UV protectant molecules and determining their efficacy for the extent of protection against Ultraviolet radiation in biological systems, identifying a new use of the compound menthyl benzoate as efficient UV protectant suitable for providing protection against the harmful effects of ultraviolet radiation and the extent of protection provided by menthyl benzoate.

Menthyl benzoate formulations for external UV protection

A formulation useful in the treatment of drug resistant bacterial infections comprising an effective amount of thymol obtained from the plant , mint oil containing an appropriate amount of monoterpenes obtained from a hybrid of and , and conventional additives. A method for producing the formulation by mixing the above ingredients and a method for the treatment of drug resistance in a patient by administration of a therapeutically effective amount of the formulation.

Formulation comprising thymol useful in the treatment of drug resistant bacterial infections

The present invention relates to a novel, insect tolerant, high yielding essential oil and menthol yielding mint plant named 'Sambhav', which is a cultivar of L.. The mint plant of the present invention has been developed as a result of planned experiments which devised a procedure for early selection of somaclonal variants at the in vitro stage of the variety of .

Mint plant named 'Sambhav'

The present invention relates a hexane bioactive fraction and obtained from the roots of an aromatic plant named commonly found in India for inhibiting the growth of drug resistant bacterial infections in humans and animals; also relates to a pharmaceutical composition comprising the bioactive extract with other additives for inhibiting the growth of drug resistant bacterial infections in humans and animals and a process for the isolation of said bioactive extract

Bioactive hexane fraction from Vetiveria zizanioides

The present invention relates to a method of treatment of fungal infections consisting essentially of a synergistic combination of plant compounds that are useful for enhancing the activity of antifungal compounds. The plant compounds, menthol and menthyl acetate, when mixed at specific concentrations, enhance the antifungal activity of the commercially available fungicides.

Method of treatment for fungal infections with a synergistic formulation of antifungal agents

A formulation useful in the treatment of drug resistant bacterial infections comprising an effective amount of thymol obtained from the plant mint oil containing an appropriate amount of monoterpenes obtained from a hybrid of and and conventional additives. A method for producing the formulation by mixing the above ingredients and a method for the treatment of drug resistance in a patient by administration of a therapeutically effective amount of the formulation.

The present invention provides a novel synergistic composition comprising extract obtained from the plant together with &dgr;-endotoxin, useful in controlling lepidopteran insects, methods for the preparation of the composition and application of the insecticidal composition to standing crops.

Process of its application against lepidopteran insects using Albizzia lebbeck plant extract and Bacilus thuriengiensis delta-endotoxin

The present invention provides a pharmaceutical composition for treating bacterial infections in patients comprising an effective amount of 3.5-dihydroxy-4-pent-4&prime;-enoyl-1&prime;-oxymethylbenzoic acid (Oenostacin) isolated from

Antibacterial composition comprising oenostacin from oenothera biennis

This invention is related to the development of strategic and novel composition comprising &agr; arteether and nalidixic acid or quinolone drugs, said composition useful as an advanced generation drug to counter the resistance development itself and having a potential to be used in treating infectious diseases and in inhibiting the resistance developed due to mutation in the gyr A gene of bacteria, particularly in those cases where drug resistant strains are known to appear very frequently.

Anti-microbial composition and method for producing the same

The invention provides a rapid in vitro method for selection of menthol rich mint genotypes from a large population of independent clones, said method comprising the steps of (i) raising a heterogeneous population of clones in vitro or by vegetative methods, (ii) transferring the plantlets/shoots to a basal medium, containing cytotoxic compounds in an amount sufficient to cause toxic effect in more than 95% of the clones, (iii) selecting surviving clones, their hardening in the glasshouse, transfer to field, reconfirmation of menthol tolerance through repeated in vitro assays, and (iv) multiplying selected clones and confirming genetic uniformity through RAPD analysis.

Growing community of inventors

Lucknow, India

Tiruppadiripuliyur Ranganathan Santha Kumar