The Penn State Research Foundation

Tingwei Ren

Manish Kumar

Woochul Song

Yue-Xiao Shen

Yu-Ming Tu

The present disclosure describes compositions and methods for preparing membrane protein nanosheets and two-dimensional crystals. In particular, the methods employ a solvent. A mixture of a polymer and a membrane protein is solubilized in the solvent, applied to a substrate, and subsequently dried to form the nanosheet or two-dimensional crystal. Applicants have surprisingly found that the membrane proteins maintain their structure when exposed to solvents during the short processing time utilized.

Organic solvent method for preparing membrane protein based nanosheets and membranes based on nanosheets

The present disclosure describes membrane compositions and methods for preparing membrane compositions. In particular, the methods employ a layer-by-layer approach to membrane preparation. The membrane compositions provide significantly enhanced membrane performance over existing commercial membranes, particularly in terms of permeability and selectivity.

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State College, PA, United States of America

Tingwei Ren