Industrial Technology Research Institute

Ting-Yu Shih

Yu-Hua Chen

Yu-Chun Liu

Jui-Hsiang Chen

Jing-Wen Tang

Lu-Chih Wang

Yi-Ting Hsieh

Chia-Chun Wang

Chia-wei Hong

Yuan-Kun Yu

Ping-Chen Chen

Ding-Zheng Lin

Jen-You Chu

Shu-Fang Chiang

Feng-Sheng Kao

Jennline Sheu

Jean-Dean Yang

Tse-Min Teng

Hui-Ling Cheng

Shu-Feng Chen

Hung-Jui Huang

Shu-Ling Wang

Chao-Chen Tien

Chia-Chen Tsai

Chia-Wei Hong

Wei Hu

A graft polymer is provided, which includes a polymer backbone with a plurality of hydroxy groups, protection group modified histidine grafted onto the side of the polymer backbone, and hydrophilic polymer having terminal reactive group grafted onto the side of the polymer backbone. The graft polymer coating can be applied to metal material to form a composite material, which can be implanted into an organism to reduce adhesion problems.

Graft polymer and composite material containing the same

A method for skin care and/or maintenance including applying or administering a preparation to a subject is provided. The preparation includes a biomedical composition, and the biomedical composition includes an effective amount of micelle, wherein the micelle includes a hyaluronic acid and/or a derivative thereof and a modified histidine. The modified histidine is grafted to at least one primary hydroxyl group of the hyaluronic acid and/or the derivative thereof, and a graft ratio of the modified histidine is 1-100%. Moreover, the hyaluronic acid and/or the derivative thereof and the modified histidine form the micelle on a weight percentage of 0.2-300:1.

Biomedical composition for skin care and/or maintenance and delaying and/or inhibiting skin aging and the use thereof

A sensing chip including a substrate, a plurality of metal nanostructures, a first surface modified layer and a second surface modified layer is provided. The metal nanostructures are disposed on the substrate. The first surface modified layer is disposed on a surface of the metal nanostructures, wherein the first surface modified layer includes a plurality of thiol group-containing molecules. The second surface modified layer is disposed on a surface of the substrate, wherein the second surface modified layer includes a plurality of silyl group-containing molecules.

Sensing chip

A polymer and a pharmaceutical composition employing the same are disclosed. The polymer includes a first repeating unit, a second repeating unit, and a third repeating unit. In particular, the first repeating unit is the second repeating unit is wherein Ris Calkyl group; and the third repeating unit is wherein X is and Y is a hydrophilic polymeric moiety.

Polymer, and pharmaceutical composition employing the same

The present disclosure provides a brush polymer, including: a linear polymer main chain; and brush structural side chains, including: a hydrophobic molecular branch, and a hydrophilic molecular branch and/or an anti-biofilm/or an anti-microbial molecular branch, wherein the linear polymer main chain is conjugated to the side chains by covalent bonds formed between a hydroxyl group and a reactive functional group, wherein the reactive functional group includes: isocyanate, carboxyl, or epoxy. The present disclosure also provides a medical application of the brush polymer.

Brush polymer and medical use thereof

Growing community of inventors

Taipei, Taiwan

Ting-Yu Shih