Cho Pharma Inc.

Ting-Chun Hung

Nan-Horng Lin

Charng-Sheng Tsai

Hong-Yang Chuang

An antibody-drug conjugate (ADC) has a structure represented by Formula (I): a pharmaceutically acceptable salt thereof wherein Ab is an antibody without glycans (i.e., the protein portion an antibody); Gand Gare glycan moieties, which may be the same or different; Cand Care conjugation moieties, which may be the same or different; Land Lare linker moieties, which may be the same or different; Dand D; are drug units which may be the same or different; and x and y are independently an integer from 0 to 8, provided that x+y&#x2260;0.

Antibody-drug conjugates

An antibody-drug conjugate (ADC) has a structure represented by Formula (I):[D-L-CnG-Ab-SgG-L-D]&#x2003;&#x2003; Formula (I)or a pharmaceutically acceptable salt thereof, wherein

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Taipei, Taiwan

Ting-Chun Hung