Laboratoires Upsa

Laboratories Upsa

Societe Anonyme: Laboratoires Upsa

Timur Gungor

Jean-Marie C Teulon

Nicole Bru-Magniez

Alix Cloarec

Francoise Camborde

The object of the present invention is a pharmaceutical composition, which comprises, as active principle, a combination of an adenosinergic agonist and a compound selected from the opiates, benzodiazepines and NMDA antagonists.

Adenosinergic agonist containing pharmaceutical composition with

The present invention relates to the derivatives of the formula ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.

1,2-Diarylindole derivatives, processes for their preparation and their

Adenosine derivatives, preparation methods and pharmaceutical

The present invention relates to the derivatives of the formula ##STR1## and their addition salts, and to their use in therapeutics as analgesics, as antihypertensives and as drugs with antiproliferative properties.

N6-[(Imidazo[1,2-a]pyridin-3-yl)ethyl]adenosines, their 5'-uronamide

The present invention relates to the derivatives of the formula ##STR1## and their tautomeric forms, as well as their addition salts, and to their use in therapeutics, especially for the treatment and prevention of cardiovascular diseases and in particular for the treatment of hypertension, cardiac insufficiency and diseases of the arterial wall, especially atherosclerosis.

Pyrazolopyrimidine derivatives which are angiotensin II receptor

Triazolopyrimidine derivatives which are angiotensin II receptor

The present invention relates to the derivatives of the formula ##STR1## and their tautomeric forms, as well as their addition salts, and to their use in therapeutics, especially for the treatment of cardiovascular diseases and in particular for the treatment of hypertension, cardiac insufficiency and diseases of the arterial wall.

Triazolopyrimidines which are angiotensin II receptor antagonists and

The present invention relates to the derivatives of the formula ##STR1## and their addition salts, and to their use in therapeutics, especially in the central nervous system as analgesics, anticonvulsants, antiepileptics, anxiolytics, antidepressants and neuroprotectors, and in the cardiovascular system as antiarrhythmics, antihypertensives and platelet aggregation inhibitors.

N.sup.6 -[3-(1-substituted)indolylethyl] adenosine 5'-carboxamides and

The present invention relates to the derivatives of the formula ##STR1## and the corresponding enantiomers and diastereoisomers and, if appropriate, their addition salts, and to their use in therapeutics, especially in the central nervous system as analgesics, anticonvulsants, antiepileptics, anxiolytics, antidepressants and neuroprotectors, and in the cardiovascular system as antiarrhythmics, antihypertensives and platelet aggregation inhibitors.

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Rueil Malmaison, France

Timur Gungor