Syngenta Participations Ag

Syngenta Corporation

Zeneca Limited

Timothy Robert Hawkes

Russell Colin Viner

Richard Dale

Michael Phillip Langford

Bernardus Theodorus Maria Vernooij

Simon Anthony James Warner

Christopher John Andrews

Glynn Mitchell

Yan Zhang

Stephen Thomas Hadfield

Paul Anthony Thompson

John M Cox

Russell Martin Ellis

Roger Barrett

Peter Bellini

Vance Cary Kramer

Jeremy Robert Godwin

Shradha Singh

Satvinder Bachoo

Simon Warner

Andrew Paul Pickerill

Elizabeth Pearson

Jose Luis Calvo

Robin Wesley

Ryan Jon Langs Ramsey

Jeremy R Godwin

Paul Richard Drayton

Bernard Theodorus Vernooij

Simon Anthony Warner

Michael Philipp Langford

Shardha Singh

Ryan Ramsey

Novel hydroxyphenyl pyruvate dioxygenase (HPPD) polypeptides, variants and fragments thereof, as well as polynucleotides encoding the same, capable of conferring commercial levels of conferring HPPD herbicide resistance or tolerance to plants. Compositions include amino acid sequences, and variants and fragments thereof, for HPPD polypeptides, as well as polynucleotides encoding the same. Methods for the production and use of HPPD herbicide resistant plants that express these novel HPPD polypeptides, methods for selectively controlling weeds in a field at a crop locus, and methods for the assay, characterization, identification and selection of these novel HPPDs are also provided.

Hydroxyphenylpyruvate dioxygenase polypeptides and methods of use

Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.

Mutant hydroxyphenylpyruvate dioxygenase polypeptides and methods of use

The present invention relates to methods comprising applying to a useful plant, the locus thereof or propagation material thereof a combination of abscisic acid and a fungicidally active compound, which fungicidally active compound is a succinate dehydrogenase inhibitor, in particular for increasing the potency of a fungicidally active compound. The invention also relates to compositions comprising abscisic acid and the fungicidally active compounds as well as seeds comprising the combinations.

Compositions comprising abscisic acid and a fungicidally active compound

A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterised in that (i) the non-phytotoxic substance is D-phosphinothricin and (ii) the enzyme is a D-amino acid oxidase.

Method of selectively producing male or female sterile plants

Methods for making transgenic plants that are resistant to HPPD herbicides are presented. Polynucleotides other than those fromthat encode resistant HPPD enzymes are enclosed for use in the process of making transgenic plants that are tolerant to HPPD-inhibiting herbicides.

Methods for the production of plants resistant to HPPD herbicides

A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterized in that (i) the non-phytotoxic substance is a D-alpha amino acid, and (ii) the enzyme is a D-amino acid oxidase.

Compositions and methods for conferring herbicide resistance or tolerance to plants, plant cells, tissues and seeds are provided. Compositions include transgenic plants, plant cells, tissues, and seeds that have been transformed with a nucleic acid molecule encoding a cytochrome P450 or variant thereof that confers herbicide resistance or tolerance, alone or in combination with one or more additional nucleic acid molecules encoding polypeptides that confer desirable traits. In particular, the cytochrome P450 or variant thereof confers resistance or tolerance to HPPD inhibitors, benzothiadiazinones, sulfonylureas, and other classes of herbicides. The additional polypeptide may also confer resistance or tolerance to an herbicide, including HPPD inhibitors and other herbicides. Methods are also provided for the production and use of the herbicide resistant or tolerant plants, plant cells, tissues and seeds of the invention.

Cytochrome P450 genes conferring herbicide resistance

Growing community of inventors

Bracknell, United Kingdom

Timothy Robert Hawkes