Medtronic, Inc.

Medtronic Vascular, Inc.

Medtronics, Inc.

Guy's and St. Thomas' Nhs Foundation Trust

Vanermen, Hugo

Timothy R Ryan

Joseph C Morrow

Charles P Tabor

Timothy G Laske

Carol Elsa Eberhardt

Alexander J Hill

Carolyn C Majkrzak

Jack D Lemmon

Michael Gloss

Brian A Glynn

Tammy Y Tam

Anne L Brody Rubin

Jerald Lamont Redmond

Michael J Tuchek

James R Keogh

Janice Lynn Shay

Matthew W Weston

Stephen T Kuehn

Timothy D Groen

Keith M Johnson

Matthew Rust

Jason L Quill

Eliot F Bloom

Cathleen A Bergin

Eugene Grossi

Mark T Stewart

David E Francischelli

Marc A Anderson

James R Skarda

Philipp Bonhoeffer

Deirdre Bridget McGowan Smyth

Don H Tran

Declan P Costello

Louis A Campbell

Hugo Vanermen

Aubrey Galloway

Cathy A Bergin

Thierry Mesana

Allen J Tower

Mark Casley

Evelyn Birmingham

Melissa R Young

Melissa Denton

J Michael Tuchek

Maria Awad

Behrooz Nadian

Rudiger Lange

Jeffrey W Allen

Wayne M Falk

Carlos M Duran

Adam Podbelski

Jose M Revuelta

Morgan House

Mark J Capps

Stuart R MacDonald

Stephen B Colvin

Ann L Brody Rubin

Maria Botrous

José M Revuelta

Tirone E David

Molly Anne Berringer

James L Rumpca

Alexander John Hill

Jason Lloren Quill

Silvia Schievano

Anne B Rubin

Declan Costello

Timothy Groen

Stella Kim

Matthew Weston

Timothy R Laske

Michael A Gloss

Thierry Georges Mesana

Vinayak Bapat

A compressible and expandable stent assembly for implantation in a body lumen such as a mitral valve, the stent assembly including at least one stent barrel that is shaped and sized so that it allows for normal operation of adjacent heart structures. One or more stent barrels can be included in the stent assembly, where one or more of the stent barrels can include a cylinder with a tapered edge.

Stented heart valve devices and methods for atrioventricular valve replacement

Delivery devices and device elements that provide steering capabilities and methods of steering such delivery devices during the delivery of a stented prosthesis to a target site. Various delivery devices include a shaft assembly having a plurality of lumens through which tension members that compressively retain the stented prosthesis to the shaft assembly are routed. By selectively tensioning one or more tension members, the shaft assembly can be pulled or steered in a desired direction. Various embodiments include one or more steering or stiffening rods that can reinforce the device or counteract any unintended bending or steering of the delivery device.

Stented prosthesis delivery devices having steering capabilities and methods

A delivery system for delivering an implantable stented device to a lumen of a patient, the delivery system including an elongated body having a proximal end and a distal end, a driver mechanism positioned at the proximal end of the elongated body, an elongated threaded rod located axially distal to the driver mechanism, and a sheath including an elongated tubular portion having a hollow interior portion with a first diameter that is sized for compression and retention of the implantable stented device in a compressed configuration for delivery to a body lumen.

Delivery systems and methods of implantation for prosthetic heart valves

Methods and apparatus for holding and maneuvering a valve during preparation and attachment to patient, providing increased visibility of the prosthetic valve and the sewing ring to prevent suture entanglement. A handle attachment is spaced from the valve for improved visibility of the sewing ring and the outlet end of the valve during attachment. Commissure posts are bent inward at the tips while preventing crashing of the commissure posts into each other causing damage. A release force needed to remove the holder and unthread the holder sutures is reduced. The holder and related methods can provide a kink free holder suture path to reduce suture entanglement and prevent damage to the implanted valve during holder removal by reducing the release force needed to remove the holder sutures by up to 30%.

Valve delivery device

A system includes a medical device for implanting in a valve of a subject, the implantable medical device having a self-expanding frame; and a holder configured to retain the frame of the implantable medical device in a constricted configuration and to control expansion of the frame. The holder has a controllably constrictable and expandable loop, wherein the loop is disposed about at least a portion of the self-expanding frame such that constriction or expansion of the first loop controls constriction or expansion of the frame.

Valve delivery tool

A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stented valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

Stents for prosthetic heart valves

Aspects of the disclosure include a prosthetic heart valve including a stent structure forming a plurality of commissure posts, a valve structure supported by the stent structure, a base supporting the stent structure and at least one radiopaque element positioned around the base. The radiopaque element can include a band extending around the base. In some embodiments the band is coiled. The band can optionally include a badge with an indicator specifying properties of the valve and viewable under fluoroscopy. In some embodiments, the radiopaque element is a badge that can have an indicator. The radiopaque elements of the disclosure increase ease and accuracy in the positioning of a percutaneously delivered replacement valve within a previously implanted valve of the disclosure.

Radiopaque elements for surgical heart valves

A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the tubular body portion.

A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

A prosthetic heart valve for functionally replacing a previously implanted prosthetic heart valve is disclosed. The prosthetic heart valve includes a collapsible support structure with leaflets and anchors mounted to the support structure. The support structure also includes an inflow end and an outflow end. The anchors include a radially outwardly extending first anchor proximate to the inflow end and a radially outwardly extending second anchor proximate to the outflow end. The first anchor includes a first configuration and the second anchor includes a second configuration where the first configuration is different than the second configuration. The previously implanted prosthetic heart valve serves as a platform for securement of the prosthetic heart valve to the patient's native tissue.

Replacement prosthetic heart valve, system and method of implant

A delivery system for an implantable stented device having a handle with a plurality of actuation members, each actuation member connected to one or more stent attachment elements, a sheath having a proximal end attached to the handle, and a plurality of tubes extending within the sheath. The stent attachment elements extend from distal ends of the tubes. A first actuation member is configured to move a first stent attachment element proximally toward the handle and a second actuation member is configured to move a second stent attachment element proximally toward the handle, sequentially releasing specific portions of the stented device by causing distal ends of the stent attachment elements to contact an exterior of the distal ends of the tubes, thereby disengaging the first and second stent attachment elements from the stented device.

Growing community of inventors

Shorewood, MN, United States of America

Timothy R Ryan