Other

The University of North Carolina at Chapel Hill

Vanderbilt University

Southern Research Institute

Timothy Patrick Sheahan

Corinne E Augelli-Szafran

Ralph Baric

Ashish Kumar Pathak

Omar Moukha-Chafiq

Syed Kaleem Ahmed

Mark R Denison

John Phillip Tillotson

Amy Catherine Sims

Chin Y Wang

Shilpa Dutta

The present disclosure is concerned with substituted phenyl ethynyl pyridine carboxamide compounds, pharmaceutical compositions comprising the compounds, and methods of treating viral infections due to a Coronavirus such as, for example, Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and severe acute respiratory syndrome coronavirus disease 2019 (SARS-CoV-2), using the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Substituted phenyl ethynyl pyridine carboxamides as potent inhibitors of SARS virus

A telephone cradle has ratcheting, sliding walls which engage a telephone and hold it securely. A ratchet release button, operable by the same hand that grasps the telephone, releases the sliding walls when it is desired to lift and use the telephone. The walls are spring-loaded to open and are driven to move equally in opposite directions. A friction plate dampens the motion of the sliding walls. Resilient pads disposed on the sliding walls securely hold the telephone. The cradle may be flexibly mounted to a vehicle.

Cradle for telephone

Growing community of inventors

Chapel Hill, NC, United States of America

Timothy Patrick Sheahan