Abbott Laboratories Corporation

Abbott Diabetes Care Inc.

Abbott Molecular Inc.

Spectrx, Inc.

Timothy P Henning

Eric B Shain

David Dean Cunningham

Douglas F Young

Thomas G Schapira

Michael G Lowery

Andrew J Muetterties

Tuan A Elstrom

Gary F Prokop

Jared L Watkin

Mark R Pope

Peter M Bojan

Joshua P Goldfarb

Geoffrey Roger Chambers

Neil W Loomis

Graham J Hughes

Yi Wang

Gamal Khalil

Thomas G Spring

Edmund T Marciniec

Mark A Talmer

Eric Yeaton

Jonathan Eppstein

Joseph P Skinner

R Hayes Helgren

Chadwick M Dunn

Sonal Sadaria Nana

Robert G Hiltibran

Timothy J Patno

Daniel J Harris

Wesley W Addison, Ii

Neal T Sleszynski

Hugh W Graham

Kenneth S Johnson

Jill M Geist

Brian Joseph Tarkowski

Jody L Keck

Kevin C Warnke

Laura S Morici

Susan B Brontman

Eric D Yeaton

Austin Lines

Kristen L Cousineau

Peter N Bojan

Wesley W Addison Ii

Aspects of the present disclosure include sample preparation cartridges including a frame that includes a plurality of wells integrated therewith, where the plurality of wells have a closed bottom and an open top. The frame further includes an opening within the frame having a reaction vessel (RV) or RV cap removably disposed therein, where the plurality of wells and the opening are linearly arranged relative to each other. Also provided are sample preparation cartridges that include a frame, two or more cartridge separation projections on a top side of the frame, and two or more cartridge separation projections on a bottom side of the frame. The cartridge separation projections separate the cartridge and a different cartridge when the cartridge and different cartridge are stacked. Methods of using the sample preparation cartridges, as well as nucleic acid sample preparation units that include the sample preparation cartridges, are also provided.

Sample preparation cartridges and methods for using same

The subject invention provides conductive stripes, suitable for use as electrodes, and methods of making conductive stripes.

Method of making, and, analyte sensor

Methods of making, and, analyte sensor

Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises:

Method and apparatus for obtaining blood for diagnostic tests

Fluid collection and monitoring device

Diagnostic test for the measurement of analyte in abiological fluid

A device for obtaining a sample of interstitial fluid from a patient for use in monitoring the level of blood glucose in the patient. The device comprises a hollow tube having a wall surrounding a cavity, wherein the wall of the tube contains a multiplicity of pores.

Device and method for obtaining interstitial fluid from a patient for diagnostic tests

Provided are microparticle forms of carbon, carbon catalysts and carbon-containing electrically conductive materials which are covalently linked to peroxidase. The carbon:peroxidase conjugates are suitable for use as substrates in conventional electrodes. Surprisingly, the conjugates display very little sensitivity to known interfering substances and thus are suitable for use as interference free electrodes.

Interference free biosensor

Removal of stratum corneum by means of light

A method and apparatus for obtaining a sample of interstitial fluid from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of (a) treating an area of the skin with vacuum or heat or both vacuum and heat to increase the availability of interstitial fluid at that area of the skin; (b) forming an opening in the treated area of the skin; and (c) extracting the sample of interstitial fluid from the opening in the skin, with the aid of vacuum and stretching of the skin. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. Th apparatus comprises (a) a device for forming an unobstructed opening in the area of the skin from which the sample is to be extracted, preferably a lancing assembly; and (b) a vacuum pump. Preferably, the apparatus also includes a housing.

Method and apparatus for obtaining interstitial fluid for diagnostic

Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of:

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Vernon Hills, IL, United States of America

Timothy P Henning