University of Utah Research Foundation

University of Southern California

Timothy Jenkins

Douglas T Carrell

Bruce Kent Gale

Raheel Samuel

Alex Jafek

Jiyoung Son

Jim Hotaling

Kenneth I Aston

Andrew David Smith

Bradley Cairns

Philip James Uren

Alan Horsager

A method for separating and enriching sperm from a tissue sample comprises: obtaining a microfluidic separating system having an inlet end and an outlet end, and a membrane filter (e.g., hollow fiber membrane filter) fluidly connected to the outlet end; separating the tissue sample via the microfluidic separating system into a debris fluid volume and a sperm fluid volume; and enriching the sperm fluid volume by removing excess media via the membrane filter. A two-stage tissue sample separation system comprising: a microchannel structure defining a separation fluid channel to form a separation stage; an inlet end of the microchannel structure; an outlet end of the microchannel structure; and a membrane filter fluidly connected to the outlet end for removal of at least a portion of excess media in the tissue sample.

Microfluidic system for sperm separation and enrichment from various types of sperm samples

Methods are provided of identifying a male fertility condition in a subject. Methods of performing a fertility treatment and an in vitro fertilization procedure are also provided. The methods may comprise determining the DNA methylation pattern of DNA extracted from a semen sample of a subject.

Methods of identifying male fertility status and embryo quality

Growing community of inventors

Salt Lake City, UT, United States of America

Timothy Jenkins